Gene description for Wdr36
Gene name WD repeat domain 36
Gene symbol Wdr36
Other names/aliases 5730444A13Rik
Ta-wdrp
Species Mus musculus
 Database cross references - Wdr36
ExoCarta ExoCarta_225348
Entrez Gene 225348
 Wdr36 identified in exosomes derived from the following tissue/cell type
Neural stem cells 25242146    
 Gene ontology annotations for Wdr36
Molecular Function
    poly(A) RNA binding GO:0044822 ISO
Biological Process
    rRNA processing GO:0006364 IBA
    regulation of axon extension GO:0030516 IMP
    retina homeostasis GO:0001895 IMP
Subcellular Localization
    Pwp2p-containing subcomplex of 90S preribosome GO:0034388 IBA
    small-subunit processome GO:0032040 IBA
    nucleolus GO:0005730 ISO
 Experiment description of studies that identified Wdr36 in exosomes
1
Experiment ID 263
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
CD63|CD9
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25242146    
Organism Mus musculus
Experiment description Extracellular Vesicles from Neural Stem Cells Transfer IFN-γ via Ifngr1 to Activate Stat1 Signaling in Target Cells
Authors Chiara Cossetti, Nunzio Iraci, Tim R. Mercer, Tommaso Leonardi, Emanuele Alpi, Denise Drago, Clara Alfaro-Cervello, Harpreet K. Saini, Matthew P. Davis, Julia Schaeffer, Beatriz Vega, Matilde Stefanini, CongJian Zhao, Werner Muller, Jose Manuel Garcia-Verdugo, Suresh Mathivanan, Angela Bachi, Anton J. Enright, John S. Mattick, Stefano Pluchino
Journal name Molecular Cell
Publication year 2014
Sample Neural stem cells
Sample name NPCs - Th1 treated
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.20 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Wdr36
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Wdr36 is involved
No pathways found





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