Gene description for Zfp59
Gene name zinc finger protein 59
Gene symbol Zfp59
Other names/aliases Mfg-2
Mfg2
Species Mus musculus
 Database cross references - Zfp59
ExoCarta ExoCarta_22717
Entrez Gene 22717
 Zfp59 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Zfp59
Molecular Function
    metal ion binding GO:0046872 IEA
    nucleic acid binding GO:0003676 IEA
    sequence-specific DNA binding transcription factor activity GO:0003700 IBA
    DNA binding GO:0003677 IEA
Biological Process
    regulation of transcription, DNA-templated GO:0006355 IBA
Subcellular Localization
    intracellular GO:0005622 IEA
    nucleus GO:0005634 IDA
 Experiment description of studies that identified Zfp59 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Zfp59
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Zfp59 is involved
No pathways found





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