Gene description for ITGA11
Gene name integrin, alpha 11
Gene symbol ITGA11
Other names/aliases HsT18964
Species Homo sapiens
 Database cross references - ITGA11
ExoCarta ExoCarta_22801
Entrez Gene 22801
HGNC 6136
MIM 604789
UniProt Q9UKX5  
 ITGA11 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells Unpublished / Not applicable
 Gene ontology annotations for ITGA11
Molecular Function
    metal ion binding GO:0046872 IEA
    collagen receptor activity GO:0038064 IMP
    collagen binding GO:0005518 IMP
    collagen binding involved in cell-matrix adhesion GO:0098639 IMP
Biological Process
    cell adhesion mediated by integrin GO:0033627 IMP
    extracellular matrix organization GO:0030198 TAS
    cell-matrix adhesion GO:0007160 IMP
    substrate-dependent cell migration GO:0006929 IMP
    osteoblast differentiation GO:0001649 IDA
    integrin-mediated signaling pathway GO:0007229 IMP
    muscle organ development GO:0007517 TAS
    collagen-activated signaling pathway GO:0038065 IMP
    cell adhesion GO:0007155 TAS
Subcellular Localization
    plasma membrane GO:0005886 TAS
    integrin complex GO:0008305 TAS
    focal adhesion GO:0005925 IDA
    membrane GO:0016020 IDA
    integrin alpha11-beta1 complex GO:0034681 IDA
 Experiment description of studies that identified ITGA11 in exosomes
1
Experiment ID 126
ISEV standards
✘ EV Biophysical techniques
✔
GAPDH
EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
 Protein-protein interactions for ITGA11
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which ITGA11 is involved
PathwayEvidenceSource
Integrin cell surface interactions TAS Reactome





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