Gene description for Osbpl2
Gene name oxysterol binding protein-like 2
Gene symbol Osbpl2
Other names/aliases C130070J12Rik
ORP-2
Orp2
mKIAA0772
Species Mus musculus
 Database cross references - Osbpl2
ExoCarta ExoCarta_228983
Entrez Gene 228983
UniProt Q8BX94  
 Osbpl2 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Osbpl2
Molecular Function
    lipid binding GO:0008289 IEA
    cholesterol binding GO:0015485 ISO
Biological Process
    biological_process GO:0008150 ND
    transport GO:0006810 IEA
    lipid transport GO:0006869 IEA
Subcellular Localization
    cellular_component GO:0005575 ND
 Experiment description of studies that identified Osbpl2 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Osbpl2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Osbpl2 is involved
No pathways found





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