Gene description for Gpr149
Gene name G protein-coupled receptor 149
Gene symbol Gpr149
Other names/aliases 9630018L10Rik
Ieda
PGR10
R35
Species Mus musculus
 Database cross references - Gpr149
ExoCarta ExoCarta_229357
Vesiclepedia VP_229357
Entrez Gene 229357
UniProt Q3UVY1  
 Gpr149 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Gpr149
Molecular Function
    G protein-coupled receptor activity GO:0004930 IBA
    G protein-coupled receptor activity GO:0004930 IEA
    neuropeptide binding GO:0042923 IBA
Biological Process
    preantral ovarian follicle growth GO:0001546 IMP
    antral ovarian follicle growth GO:0001547 IMP
    G protein-coupled receptor signaling pathway GO:0007186 IEA
    neuropeptide signaling pathway GO:0007218 IBA
    estrous cycle phase GO:0060206 IMP
    negative regulation of ovulation GO:0060280 IMP
Subcellular Localization
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 IEA
    neuron projection GO:0043005 IBA
 Experiment description of studies that identified Gpr149 in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Gpr149
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Gpr149 is involved
No pathways found





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