Gene description for Gbp7
Gene name guanylate binding protein 7
Gene symbol Gbp7
Other names/aliases 9830147J24Rik
Species Mus musculus
 Database cross references - Gbp7
ExoCarta ExoCarta_229900
Entrez Gene 229900
 Gbp7 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Gbp7
Molecular Function
    molecular_function GO:0003674 ND
Biological Process
    defense response to Gram-positive bacterium GO:0050830 IDA
    adhesion of symbiont to host GO:0044406 IDA
    defense response to protozoan GO:0042832 IMP
    cellular response to interferon-gamma GO:0071346 IDA
Subcellular Localization
    cytoplasmic vesicle GO:0031410 IDA
    symbiont-containing vacuole membrane GO:0020005 IDA
 Experiment description of studies that identified Gbp7 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Gbp7
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Gbp7 is involved
No pathways found





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