Gene description for Car9
Gene name carbonic anhydrase 9
Gene symbol Car9
Other names/aliases CAIX
Species Mus musculus
 Database cross references - Car9
ExoCarta ExoCarta_230099
Entrez Gene 230099
UniProt Q8VHB5  
 Car9 identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Car9
Molecular Function
    zinc ion binding GO:0008270 IEA
    metal ion binding GO:0046872 IEA
    lyase activity GO:0016829 IEA
    carbonate dehydratase activity GO:0004089 IEA
Biological Process
    morphogenesis of an epithelium GO:0002009 IMP
    secretion GO:0046903 IMP
    one-carbon metabolic process GO:0006730 IEA
Subcellular Localization
    cell projection GO:0042995 IEA
    membrane GO:0016020 IEA
    integral component of membrane GO:0016021 IEA
    plasma membrane GO:0005886 ISO
    basolateral plasma membrane GO:0016323 ISO
 Experiment description of studies that identified Car9 in exosomes
Experiment ID 210
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Car9
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Car9 is involved
Reversible hydration of carbon dioxide IEA Reactome

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