Gene description for Car9
Gene name carbonic anhydrase 9
Gene symbol Car9
Other names/aliases CAIX
Ca9
MN/CA9
Species Mus musculus
 Database cross references - Car9
ExoCarta ExoCarta_230099
Entrez Gene 230099
UniProt Q8VHB5  
 Car9 identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Car9
Molecular Function
    zinc ion binding GO:0008270 IEA
    metal ion binding GO:0046872 IEA
    lyase activity GO:0016829 IEA
    carbonate dehydratase activity GO:0004089 IEA
Biological Process
    morphogenesis of an epithelium GO:0002009 IMP
    secretion GO:0046903 IMP
    one-carbon metabolic process GO:0006730 IEA
Subcellular Localization
    cell projection GO:0042995 IEA
    membrane GO:0016020 IEA
    integral component of membrane GO:0016021 IEA
    plasma membrane GO:0005886 ISO
    basolateral plasma membrane GO:0016323 ISO
 Experiment description of studies that identified Car9 in exosomes
1
Experiment ID 210
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✔
CD81|FLOT1
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Car9
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Car9 is involved
PathwayEvidenceSource
Reversible hydration of carbon dioxide IEA Reactome





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