Gene description for Pabpc4
Gene name poly(A) binding protein, cytoplasmic 4
Gene symbol Pabpc4
Other names/aliases -
Species Mus musculus
 Database cross references - Pabpc4
ExoCarta ExoCarta_230721
Vesiclepedia VP_230721
Entrez Gene 230721
 Pabpc4 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Pabpc4
Molecular Function
    mRNA binding GO:0003729 IDA
    mRNA 3'-UTR binding GO:0003730 IBA
    poly(A) binding GO:0008143 IBA
    poly(A) binding GO:0008143 ISO
    poly(U) RNA binding GO:0008266 IBA
    poly(U) RNA binding GO:0008266 ISO
    poly(C) RNA binding GO:0017130 ISO
Biological Process
    regulation of mRNA stability GO:0043488 IMP
    myeloid cell development GO:0061515 IMP
Subcellular Localization
    nucleus GO:0005634 IBA
    nucleus GO:0005634 ISO
    cytoplasm GO:0005737 ISO
    cytosol GO:0005829 IBA
    cytosol GO:0005829 ISO
    cytoplasmic stress granule GO:0010494 IBA
    cytoplasmic stress granule GO:0010494 ISO
    ribonucleoprotein complex GO:1990904 IBA
    ribonucleoprotein complex GO:1990904 ISO
 Experiment description of studies that identified Pabpc4 in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Pabpc4
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Kctd13  
Affinity Capture-MS Mus musculus
View the network image/svg+xml
 Pathways in which Pabpc4 is involved
No pathways found





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