Gene description for Pabpc4
Gene name poly(A) binding protein, cytoplasmic 4
Gene symbol Pabpc4
Other names/aliases -
Species Mus musculus
 Database cross references - Pabpc4
ExoCarta ExoCarta_230721
Entrez Gene 230721
 Pabpc4 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Pabpc4
Molecular Function
    poly(A) RNA binding GO:0044822 ISO
    poly(C) RNA binding GO:0017130 ISO
    poly(A) binding GO:0008143 ISO
    poly(U) RNA binding GO:0008266 ISO
Biological Process
    biological_process GO:0008150 ND
Subcellular Localization
    nucleus GO:0005634 ISO
    cytoplasmic stress granule GO:0010494 ISO
    cytoplasm GO:0005737 ISO
    ribonucleoprotein complex GO:0030529 ISO
 Experiment description of studies that identified Pabpc4 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Pabpc4
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Pabpc4 is involved
No pathways found





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