Gene description for Ythdc1
Gene name YTH domain containing 1
Gene symbol Ythdc1
Other names/aliases A730098D12Rik
C80342
mKIAA1966
Species Mus musculus
 Database cross references - Ythdc1
ExoCarta ExoCarta_231386
Entrez Gene 231386
UniProt E9Q5K9  
 Ythdc1 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Ythdc1
Molecular Function
    N6-methyladenosine-containing RNA binding GO:1990247 ISO
    poly(A) RNA binding GO:0044822 ISO
    RNA binding GO:0003723 ISO
Biological Process
    mRNA splicing, via spliceosome GO:0000398 ISO
    RNA splicing GO:0008380 IEA
    mRNA processing GO:0006397 IEA
    mRNA splice site selection GO:0006376 ISO
Subcellular Localization
    nucleus GO:0005634 ISO
    nuclear body GO:0016604 ISO
    nucleoplasm GO:0005654 ISO
 Experiment description of studies that identified Ythdc1 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Ythdc1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Ythdc1 is involved
No pathways found





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