Gene description for Mob1a
Gene name MOB kinase activator 1A
Gene symbol Mob1a
Other names/aliases 4022402H07Rik
MOB1
MOB4B
Mobk1b
Mobkl1b
Species Mus musculus
 Database cross references - Mob1a
ExoCarta ExoCarta_232157
Entrez Gene 232157
UniProt Q921Y0  
 Mob1a identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Mob1a
Molecular Function
    metal ion binding GO:0046872 IEA
Biological Process
    hippo signaling GO:0035329 ISO
Subcellular Localization
    extracellular exosome GO:0070062 ISO
    intracellular GO:0005622 ISO
 Experiment description of studies that identified Mob1a in exosomes
1
Experiment ID 15
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Mob1a
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Mob1a is involved
PathwayEvidenceSource
Signaling by Hippo IEA Reactome





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here