Gene description for Pyroxd1
Gene name pyridine nucleotide-disulphide oxidoreductase domain 1
Gene symbol Pyroxd1
Other names/aliases -
Species Mus musculus
 Database cross references - Pyroxd1
ExoCarta ExoCarta_232491
Vesiclepedia VP_232491
Entrez Gene 232491
UniProt Q3TMV7  
 Pyroxd1 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Pyroxd1
Molecular Function
    molecular_function GO:0003674 ND
    oxidoreductase activity GO:0016491 IEA
Biological Process
    cellular response to oxidative stress GO:0034599 ISO
    cellular response to oxidative stress GO:0034599 ISS
Subcellular Localization
    nucleus GO:0005634 IDA
    nucleus GO:0005634 ISO
    nucleus GO:0005634 ISS
    cytoplasm GO:0005737 IDA
    sarcomere GO:0030017 ISO
    sarcomere GO:0030017 ISS
 Experiment description of studies that identified Pyroxd1 in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Pyroxd1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Pyroxd1 is involved
No pathways found





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