Gene description for Cd109
Gene name CD109 antigen
Gene symbol Cd109
Other names/aliases 9930012E15Rik
Species Mus musculus
 Database cross references - Cd109
ExoCarta ExoCarta_235505
Entrez Gene 235505
UniProt Q8R422  
 Cd109 identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Cd109
Molecular Function
    peptidase inhibitor activity GO:0030414 IEA
    endopeptidase inhibitor activity GO:0004866 IEA
    serine-type endopeptidase inhibitor activity GO:0004867 IEA
    transforming growth factor beta binding GO:0050431 ISO
Biological Process
    osteoclast fusion GO:0072675 IMP
    negative regulation of protein phosphorylation GO:0001933 IMP
    negative regulation of peptidase activity GO:0010466 IEA
    regulation of keratinocyte differentiation GO:0045616 IMP
    negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 ISO
    hair follicle development GO:0001942 IMP
    negative regulation of keratinocyte proliferation GO:0010839 IMP
    negative regulation of wound healing GO:0061045 ISO
Subcellular Localization
    extracellular region GO:0005576 IEA
    anchored component of membrane GO:0031225 IEA
    cell surface GO:0009986 ISO
    membrane GO:0016020 IEA
    plasma membrane GO:0005886 IEA
    extracellular space GO:0005615 IEA
 Experiment description of studies that identified Cd109 in exosomes
Experiment ID 210
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Cd109
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Cd109 is involved
No pathways found

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