Gene description for Tusc5
Gene name tumor suppressor candidate 5
Gene symbol Tusc5
Other names/aliases C130069F04Rik
DSPB1
Lost1
Species Mus musculus
 Database cross references - Tusc5
ExoCarta ExoCarta_237858
Entrez Gene 237858
UniProt Q8C838  
 Tusc5 identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Tusc5
Molecular Function
    molecular_function GO:0003674 ND
Biological Process
    response to biotic stimulus GO:0009607 IEA
    biological_process GO:0008150 ND
Subcellular Localization
    cellular_component GO:0005575 ND
    integral component of membrane GO:0016021 IEA
    membrane GO:0016020 IEA
 Experiment description of studies that identified Tusc5 in exosomes
1
Experiment ID 210
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD81|FLOT1
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Tusc5
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Tusc5 is involved
No pathways found





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