Gene description for Dock4
Gene name	dedicator of cytokinesis 4
Gene symbol	Dock4
Other names/aliases	5330406C03 6330411N01Rik AF263288 C030023J22 mKIAA0716
Species	Mus musculus
Database cross references - Dock4
ExoCarta	ExoCarta_238130
Vesiclepedia	VP_238130
Entrez Gene	238130
UniProt	P59764
Dock4 identified in sEVs derived from the following tissue/cell type
Mast cells	17486113

Gene ontology annotations for Dock4

Molecular Function     guanyl-nucleotide exchange factor activity GO:0005085 IBA     guanyl-nucleotide exchange factor activity GO:0005085 ISO     guanyl-nucleotide exchange factor activity GO:0005085 ISS     GTPase activator activity GO:0005096 IEA     SH3 domain binding GO:0017124 IEA     PDZ domain binding GO:0030165 IEA     PDZ domain binding GO:0030165 ISO     receptor tyrosine kinase binding GO:0030971 IEA     receptor tyrosine kinase binding GO:0030971 ISO     small GTPase binding GO:0031267 IBA     small GTPase binding GO:0031267 IEA     small GTPase binding GO:0031267 ISO Biological Process     small GTPase-mediated signal transduction GO:0007264 IEA     cell chemotaxis GO:0060326 IBA     cell chemotaxis GO:0060326 ISO     cell chemotaxis GO:0060326 ISS     regulation of postsynapse assembly GO:0150052 IEA     negative regulation of vascular associated smooth muscle contraction GO:1904694 IEA     negative regulation of vascular associated smooth muscle contraction GO:1904694 ISO     positive regulation of vascular associated smooth muscle cell migration GO:1904754 IEA     positive regulation of vascular associated smooth muscle cell migration GO:1904754 ISO Subcellular Localization     nucleolus GO:0005730 IEA     nucleolus GO:0005730 ISO     cytoplasm GO:0005737 IBA     Golgi apparatus GO:0005794 IEA     Golgi apparatus GO:0005794 ISO     cytosol GO:0005829 ISO     cytosol GO:0005829 ISS     plasma membrane GO:0005886 IBA     plasma membrane GO:0005886 IEA     plasma membrane GO:0005886 ISO     membrane GO:0016020 ISO     membrane GO:0016020 ISS     stereocilium GO:0032420 IDA     stereocilium bundle GO:0032421 IDA     postsynapse GO:0098794 IEA     glutamatergic synapse GO:0098978 IEA