Gene description for Colec10
Gene name collectin sub-family member 10
Gene symbol Colec10
Other names/aliases CL-L1
Species Mus musculus
 Database cross references - Colec10
ExoCarta ExoCarta_239447
Vesiclepedia VP_239447
Entrez Gene 239447
UniProt Q8CF98  
 Colec10 identified in sEVs derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Colec10
Molecular Function
    D-mannose binding GO:0005537 IDA
    chemoattractant activity GO:0042056 IEA
    chemoattractant activity GO:0042056 ISO
Biological Process
    complement activation, lectin pathway GO:0001867 IEA
    complement activation, lectin pathway GO:0001867 ISO
    proteolysis GO:0006508 IEA
    proteolysis GO:0006508 ISO
    defense response GO:0006952 NAS
    heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules GO:0007157 NAS
    embryo development ending in birth or egg hatching GO:0009792 NAS
    positive chemotaxis GO:0050918 IEA
    positive regulation of opsonization GO:1903028 IEA
    positive regulation of opsonization GO:1903028 ISO
    cranial skeletal system development GO:1904888 IEA
    cranial skeletal system development GO:1904888 ISO
Subcellular Localization
    collagen trimer GO:0005581 IEA
    extracellular space GO:0005615 IBA
    extracellular space GO:0005615 IEA
    extracellular space GO:0005615 ISO
    nucleus GO:0005634 NAS
    cytoplasm GO:0005737 ISO
    Golgi apparatus GO:0005794 IEA
    cytosol GO:0005829 NAS
 Experiment description of studies that identified Colec10 in sEVs
1
Experiment ID 907
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Colec10
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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