Gene description for Tenm2
Gene name teneurin transmembrane protein 2
Gene symbol Tenm2
Other names/aliases Odz2
Odz3
Ten-2
Ten-m2
Species Mus musculus
 Database cross references - Tenm2
ExoCarta ExoCarta_23964
Vesiclepedia VP_23964
Entrez Gene 23964
 Tenm2 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Tenm2
Molecular Function
    signaling receptor binding GO:0005102 ISO
    signaling receptor binding GO:0005102 ISS
    protein binding GO:0005515 IPI
    identical protein binding GO:0042802 IPI
    protein homodimerization activity GO:0042803 IBA
    protein homodimerization activity GO:0042803 IDA
    protein heterodimerization activity GO:0046982 IBA
    protein heterodimerization activity GO:0046982 IDA
    cell adhesion molecule binding GO:0050839 IBA
    cell adhesion molecule binding GO:0050839 ISO
    cell adhesion molecule binding GO:0050839 ISS
Biological Process
    negative regulation of transcription by RNA polymerase II GO:0000122 ISS
    heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules GO:0007157 ISO
    signal transduction GO:0007165 IEA
    neuron development GO:0048666 IBA
    positive regulation of filopodium assembly GO:0051491 ISS
    cell-cell adhesion GO:0098609 ISS
    retrograde trans-synaptic signaling by trans-synaptic protein complex GO:0098942 ISO
Subcellular Localization
    nucleus GO:0005634 ISS
    endoplasmic reticulum GO:0005783 ISS
    Golgi apparatus GO:0005794 ISS
    plasma membrane GO:0005886 ISO
    plasma membrane GO:0005886 ISS
    cell-cell junction GO:0005911 ISO
    cell-cell junction GO:0005911 ISS
    PML body GO:0016605 ISS
    cell junction GO:0030054 ISS
    filopodium GO:0030175 ISS
    dendrite GO:0030425 ISS
    growth cone GO:0030426 ISS
    neuron projection GO:0043005 IBA
    neuron projection GO:0043005 ISO
    neuron projection GO:0043005 ISS
    dendritic spine GO:0043197 ISO
    dendritic spine GO:0043197 ISS
    synapse GO:0045202 ISO
    synapse GO:0045202 ISS
    postsynaptic membrane GO:0045211 ISO
    postsynaptic membrane GO:0045211 ISS
    extrinsic component of postsynaptic membrane GO:0098890 ISO
    glutamatergic synapse GO:0098978 ISO
 Experiment description of studies that identified Tenm2 in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Tenm2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Tsc1  
Affinity Capture-MS Mus musculus
2 Ccdc173  
Co-fractionation Mus musculus
View the network image/svg+xml
 Pathways in which Tenm2 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here