Gene description for Tenm2
Gene name teneurin transmembrane protein 2
Gene symbol Tenm2
Other names/aliases Odz2
Odz3
Ten-2
Ten-m2
Species Mus musculus
 Database cross references - Tenm2
ExoCarta ExoCarta_23964
Entrez Gene 23964
 Tenm2 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Tenm2
Molecular Function
    cell adhesion molecule binding GO:0050839 ISO
    protein homodimerization activity GO:0042803 IDA
    receptor binding GO:0005102 ISO
    protein heterodimerization activity GO:0046982 IDA
Biological Process
    heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules GO:0007157 ISO
    transcription, DNA-templated GO:0006351 IEA
    regulation of transcription, DNA-templated GO:0006355 IEA
    cell adhesion GO:0007155 IEA
    signal transduction GO:0007165 IEA
    axon guidance GO:0007411 ISO
    self proteolysis GO:0097264 IEA
    calcium-mediated signaling using intracellular calcium source GO:0035584 ISO
Subcellular Localization
    cell projection GO:0042995 IEA
    dendritic spine GO:0043197 ISO
    postsynaptic membrane GO:0045211 ISO
    neuron projection GO:0043005 ISO
    plasma membrane GO:0005886 ISO
    integral component of membrane GO:0016021 IEA
    membrane GO:0016020 IEA
    endoplasmic reticulum GO:0005783 IEA
    cell-cell junction GO:0005911 ISO
    integral component of plasma membrane GO:0005887 ISS
    nucleus GO:0005634 IEA
    Golgi apparatus GO:0005794 IEA
    synapse GO:0045202 ISO
    cell junction GO:0030054 IEA
    intracellular GO:0005622 ISO
 Experiment description of studies that identified Tenm2 in exosomes
1
Experiment ID 15
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Tenm2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Tenm2 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here