Gene description for Pnpla7
Gene name patatin-like phospholipase domain containing 7
Gene symbol Pnpla7
Other names/aliases BC027342
E430013P11Rik
Nre
Species Mus musculus
 Database cross references - Pnpla7
ExoCarta ExoCarta_241274
Entrez Gene 241274
UniProt A2AJ88  
 Pnpla7 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Pnpla7
Molecular Function
    3,4-dihydrocoumarin hydrolase activity GO:0018733 IEA
    lysophospholipase activity GO:0004622 IDA
    lipase activity GO:0016298 IEA
    methyl salicylate esterase activity GO:0080031 IEA
    Cys-tRNA(Pro) hydrolase activity GO:0043907 IEA
    endosulfan lactone lactonase activity GO:0034892 IEA
    phospholipase activity GO:0004620 IEA
    methyl indole-3-acetate esterase activity GO:0080030 IEA
    sulfolactone hydrolase activity GO:0018732 IEA
    all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity GO:0047376 IEA
    mannosyl-oligosaccharide 1,6-alpha-mannosidase activity GO:0052767 IEA
    1-oxa-2-oxocycloheptane lactonase activity GO:0018731 IEA
    methyl jasmonate esterase activity GO:0080032 IEA
    L-ascorbate 6-phosphate lactonase activity GO:0035460 IEA
    carboxylic ester hydrolase activity GO:0052689 ISO
    retinyl-palmitate esterase activity GO:0050253 IEA
    prenylcysteine methylesterase activity GO:0010296 IEA
    Ala-tRNA(Pro) hydrolase activity GO:0043906 IEA
    Ser-tRNA(Thr) hydrolase activity GO:0043905 IEA
    hydrolase activity GO:0016787 IEA
    Ser(Gly)-tRNA(Ala) hydrolase activity GO:0043908 IEA
    mannosyl-oligosaccharide 1,3-alpha-mannosidase activity GO:0052768 IEA
    butyrolactone hydrolase activity GO:0018734 IEA
Biological Process
    metabolic process GO:0008152 IEA
    developmental process GO:0032502 IBA
    lipid metabolic process GO:0006629 IEA
Subcellular Localization
    endoplasmic reticulum GO:0005783 IDA
    intracellular membrane-bounded organelle GO:0043231 IEA
    mitochondrion GO:0005739 IEA
    lysosome GO:0005764 IEA
    membrane GO:0016020 IEA
    integral component of membrane GO:0016021 IEA
    nucleus GO:0005634 IEA
 Experiment description of studies that identified Pnpla7 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Pnpla7
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Pnpla7 is involved
No pathways found





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