Gene description for Acaa1a
Gene name acetyl-CoA acyltransferase 1
Gene symbol Acaa1a
Other names/aliases Acaa
Acaa1
Pktaa
Species Rattus norvegicus
 Database cross references - Acaa1a
ExoCarta ExoCarta_24157
Entrez Gene 24157
UniProt P21775  
 Acaa1a identified in exosomes derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Acaa1a
Molecular Function
    palmitoyl-CoA oxidase activity GO:0016401 ISO
    acetyl-CoA C-acyltransferase activity GO:0003988 IEA
    transferase activity, transferring acyl groups other than amino-acyl groups GO:0016747 IEA
Biological Process
    response to steroid hormone GO:0048545 IDA
    very long-chain fatty acid metabolic process GO:0000038 ISO
    fatty acid beta-oxidation GO:0006635 ISO
    bile acid metabolic process GO:0008206 ISO
    response to drug GO:0042493 IEP
    metabolic process GO:0008152 IEA
    response to nutrient GO:0007584 IDA
Subcellular Localization
    mitochondrion GO:0005739 ISO
    peroxisome GO:0005777 ISO
    intracellular membrane-bounded organelle GO:0043231 ISO
    membrane GO:0016020 ISO
 Experiment description of studies that identified Acaa1a in exosomes
1
Experiment ID 90
ISEV standards
EM
EV Biophysical techniques
HSC70|HSP90|TSG101
EV Cytosolic markers
MHCI
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D2 Rep 1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Acaa1a
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Acaa1a is involved
No pathways found





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