Gene description for Ada
Gene name	adenosine deaminase
Gene symbol	Ada
Other names/aliases	-
Species	Rattus norvegicus
Database cross references - Ada
ExoCarta	ExoCarta_24165
Entrez Gene	24165
UniProt	Q920P6
Ada identified in exosomes derived from the following tissue/cell type
Pancreatic cancer cells	20124479
Pancreatic cancer cells	20124479

Gene ontology annotations for Ada

Molecular Function     adenosine deaminase activity GO:0004000 ISS     zinc ion binding GO:0008270 ISS     purine nucleoside binding GO:0001883 IDA Biological Process     dATP catabolic process GO:0046061 ISO     regulation of T cell differentiation GO:0045580 ISO     positive regulation of calcium-mediated signaling GO:0050850 ISO     regulation of cell-cell adhesion mediated by integrin GO:0033632 ISO     hypoxanthine biosynthetic process GO:0046101 ISO     negative regulation of mature B cell apoptotic process GO:0002906 ISO     T cell activation GO:0042110 ISO     positive regulation of T cell receptor signaling pathway GO:0050862 ISO     negative regulation of mucus secretion GO:0070256 ISO     positive regulation of B cell proliferation GO:0030890 ISO     response to vitamin E GO:0033197 IDA     negative regulation of circadian sleep/wake cycle, non-REM sleep GO:0042323 IMP     negative regulation of penile erection GO:0060407 ISO     positive regulation of T cell differentiation in thymus GO:0033089 ISO     adenosine catabolic process GO:0006154 ISS     negative regulation of leukocyte migration GO:0002686 ISO     adenosine metabolic process GO:0046085 TAS     purine ribonucleoside monophosphate biosynthetic process GO:0009168 IEA     lung alveolus development GO:0048286 ISO     inosine biosynthetic process GO:0046103 ISS     histamine secretion GO:0001821 IMP     response to hypoxia GO:0001666 ISO     negative regulation of inflammatory response GO:0050728 ISO     deoxyadenosine catabolic process GO:0006157 ISO     response to drug GO:0042493 IEP     negative regulation of apoptotic process GO:0043066 ISO     aging GO:0007568 IEP     positive regulation of T cell activation GO:0050870 ISO     embryonic digestive tract development GO:0048566 ISO     positive regulation of heart rate GO:0010460 ISO     response to morphine GO:0043278 IMP     trophectodermal cell differentiation GO:0001829 ISO     regulation of circadian sleep/wake cycle, sleep GO:0045187 IEP     Peyer's patch development GO:0048541 ISO     positive regulation of smooth muscle contraction GO:0045987 ISO     germinal center B cell differentiation GO:0002314 ISO     positive regulation of T cell differentiation GO:0045582 ISO     response to hydrogen peroxide GO:0042542 IEP     purine nucleotide salvage GO:0032261 ISO     in utero embryonic development GO:0001701 ISO     negative regulation of thymocyte apoptotic process GO:0070244 ISO     lung development GO:0030324 ISO     xanthine biosynthetic process GO:0046111 ISO     positive regulation of germinal center formation GO:0002636 ISO     liver development GO:0001889 ISO     placenta development GO:0001890 ISO     negative regulation of adenosine receptor signaling pathway GO:0060169 ISO     hypoxanthine salvage GO:0043103 IBA     positive regulation of alpha-beta T cell differentiation GO:0046638 ISO Subcellular Localization     membrane GO:0016020 ISO     cytoplasm GO:0005737 ISO     plasma membrane GO:0005886 ISO     cytoplasmic membrane-bounded vesicle lumen GO:0060205 IEA     external side of plasma membrane GO:0009897 ISO     dendrite cytoplasm GO:0032839 IDA     cell surface GO:0009986 ISO     cell junction GO:0030054 IEA     extracellular space GO:0005615 IDA     lysosome GO:0005764 ISO     neuronal cell body GO:0043025 IDA