Gene description for Adh1
Gene name alcohol dehydrogenase 1 (class I)
Gene symbol Adh1
Other names/aliases Adh
Adh1a
Adh1c
Species Rattus norvegicus
 Database cross references - Adh1
ExoCarta ExoCarta_24172
Vesiclepedia VP_24172
Entrez Gene 24172
UniProt P06757  
 Adh1 identified in sEVs derived from the following tissue/cell type
Hepatocytes 19367702    
 Gene ontology annotations for Adh1
Molecular Function
    alcohol dehydrogenase (NAD+) activity GO:0004022 IBA
    alcohol dehydrogenase (NAD+) activity GO:0004022 IDA
    alcohol dehydrogenase (NAD+) activity GO:0004022 IEA
    alcohol dehydrogenase (NAD+) activity GO:0004022 ISO
    alcohol dehydrogenase (NAD+) activity GO:0004022 TAS
    all-trans-retinol dehydrogenase (NAD+) activity GO:0004745 IBA
    all-trans-retinol dehydrogenase (NAD+) activity GO:0004745 IDA
    zinc ion binding GO:0008270 IBA
    zinc ion binding GO:0008270 IEA
    oxidoreductase activity GO:0016491 IEA
    identical protein binding GO:0042802 IEA
    identical protein binding GO:0042802 ISO
    organic cyclic compound binding GO:0097159 IPI
Biological Process
    retinoid metabolic process GO:0001523 ISO
    ethanol catabolic process GO:0006068 IEA
    ethanol catabolic process GO:0006068 ISO
    lipid metabolic process GO:0006629 IDA
    animal organ regeneration GO:0031100 IEP
    response to retinoic acid GO:0032526 IEA
    response to retinoic acid GO:0032526 ISO
    response to progesterone GO:0032570 IEP
    response to testosterone GO:0033574 IEA
    response to testosterone GO:0033574 ISO
    retinol metabolic process GO:0042572 IBA
    retinol metabolic process GO:0042572 IEA
    retinol metabolic process GO:0042572 ISO
    retinoic acid metabolic process GO:0042573 IBA
    retinoic acid metabolic process GO:0042573 IEA
    retinoic acid metabolic process GO:0042573 ISO
    response to ethanol GO:0045471 IEP
    behavioral response to ethanol GO:0048149 IEA
    behavioral response to ethanol GO:0048149 ISO
    response to steroid hormone GO:0048545 IEA
    response to steroid hormone GO:0048545 ISO
Subcellular Localization
    nucleoplasm GO:0005654 ISO
    mitochondrion GO:0005739 IEA
    mitochondrion GO:0005739 ISO
    cytosol GO:0005829 IBA
    cytosol GO:0005829 ISO
    plasma membrane GO:0005886 ISO
 Experiment description of studies that identified Adh1 in sEVs
1
Experiment ID 35
MISEV standards
CEM
Biophysical techniques
TSG101|Alix|CD81|CD63
Enriched markers
HSPA5
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19367702    
Organism Rattus norvegicus
Experiment description Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes.
Authors "Conde-Vancells J, Rodriguez-Suarez E, Embade N, Gil D, Matthiesen R, Valle M, Elortza F, Lu SC, Mato JM, Falcon-Perez JM"
Journal name JPR
Publication year 2008
Sample Hepatocytes
Sample name Hepatocytes
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
 Protein-protein interactions for Adh1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here