Gene description for Adh1
Gene name alcohol dehydrogenase 1 (class I)
Gene symbol Adh1
Other names/aliases Adh
Adh1a
Adh1c
Species Rattus norvegicus
 Database cross references - Adh1
ExoCarta ExoCarta_24172
Entrez Gene 24172
UniProt P06757  
 Adh1 identified in exosomes derived from the following tissue/cell type
Hepatocytes 19367702    
 Gene ontology annotations for Adh1
Molecular Function
    drug binding GO:0008144 IPI
    protein homodimerization activity GO:0042803 ISO
    oxidoreductase activity GO:0016491 IEA
    alcohol dehydrogenase (NAD) activity GO:0004022 TAS
    zinc ion binding GO:0008270 ISO
    alcohol dehydrogenase activity, zinc-dependent GO:0004024 ISO
    retinol dehydrogenase activity GO:0004745 IDA
    NAD binding GO:0051287 IDA
    ethanol binding GO:0035276 IDA
Biological Process
    response to testosterone GO:0033574 ISO
    retinol metabolic process GO:0042572 ISO
    response to progesterone GO:0032570 IEP
    acetaldehyde biosynthetic process GO:0046186 IDA
    retinoid metabolic process GO:0001523 ISO
    retinoic acid metabolic process GO:0042573 ISO
    oxidation-reduction process GO:0055114 ISO
    organ regeneration GO:0031100 IEP
    behavioral response to ethanol GO:0048149 ISO
    ethanol catabolic process GO:0006068 ISO
    response to steroid hormone GO:0048545 ISO
    response to retinoic acid GO:0032526 ISO
    ethanol oxidation GO:0006069 ISO
Subcellular Localization
    intracellular GO:0005622 ISO
    mitochondrion GO:0005739 ISO
    cytosol GO:0005829 IDA
 Experiment description of studies that identified Adh1 in exosomes
1
Experiment ID 35
ISEV standards
✔
CEM
EV Biophysical techniques
✔
TSG101|Alix
EV Cytosolic markers
✔
CD81|CD63
EV Membrane markers
✔
HSPA5
EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19367702    
Organism Rattus norvegicus
Experiment description Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes.
Authors Conde-Vancells J, Rodriguez-Suarez E, Embade N, Gil D, Matthiesen R, Valle M, Elortza F, Lu SC, Mato JM, Falcon-Perez JM
Journal name JPR
Publication year 2008
Sample Hepatocytes
Sample name Hepatocytes
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
 Protein-protein interactions for Adh1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Adh1 is involved
No pathways found





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