Gene description for Aldh1a1
Gene name	aldehyde dehydrogenase 1 family, member A1
Gene symbol	Aldh1a1
Other names/aliases	Ahd2 Aldh1 Aldh2
Species	Rattus norvegicus
Database cross references - Aldh1a1
ExoCarta	ExoCarta_24188
Vesiclepedia	VP_24188
Entrez Gene	24188
UniProt	P51647
Aldh1a1 identified in sEVs derived from the following tissue/cell type
Pancreatic cancer cells	20124479
Pancreatic cancer cells	20124479

Gene ontology annotations for Aldh1a1

Molecular Function     retinal dehydrogenase activity GO:0001758 IDA     3-chloroallyl aldehyde dehydrogenase activity GO:0004028 IEA     3-chloroallyl aldehyde dehydrogenase activity GO:0004028 ISO     3-chloroallyl aldehyde dehydrogenase activity GO:0004028 TAS     aldehyde dehydrogenase (NAD+) activity GO:0004029 IDA     aldehyde dehydrogenase (NAD+) activity GO:0004029 IMP     aldehyde dehydrogenase (NAD+) activity GO:0004029 ISO     oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor GO:0016620 IEA     benzaldehyde dehydrogenase (NAD+) activity GO:0018479 IBA     benzaldehyde dehydrogenase (NAD+) activity GO:0018479 IDA     aminobutyraldehyde dehydrogenase (NAD+) activity GO:0019145 IEA     aminobutyraldehyde dehydrogenase (NAD+) activity GO:0019145 ISO     aminobutyraldehyde dehydrogenase (NAD+) activity GO:0019145 ISS     identical protein binding GO:0042802 IPI     NAD binding GO:0051287 ISS     3-deoxyglucosone dehydrogenase activity GO:0106373 ISO     3-deoxyglucosone dehydrogenase activity GO:0106373 ISS Biological Process     retinoid metabolic process GO:0001523 IDA     kidney development GO:0001822 IEP     liver development GO:0001889 IEP     optic cup morphogenesis involved in camera-type eye development GO:0002072 IEA     optic cup morphogenesis involved in camera-type eye development GO:0002072 ISO     retinoic acid biosynthetic process GO:0002138 IMP     fructose catabolic process GO:0006001 IEA     fructose catabolic process GO:0006001 ISO     apoptotic process GO:0006915 IEA     apoptotic process GO:0006915 ISO     response to oxidative stress GO:0006979 IMP     midgut development GO:0007494 IEP     response to xenobiotic stimulus GO:0009410 IEA     response to xenobiotic stimulus GO:0009410 IEP     response to xenobiotic stimulus GO:0009410 ISO     gamma-aminobutyric acid biosynthetic process GO:0009449 IEA     gamma-aminobutyric acid biosynthetic process GO:0009449 ISO     gamma-aminobutyric acid biosynthetic process GO:0009449 ISS     response to organic cyclic compound GO:0014070 IEP     fructosamine catabolic process GO:0030392 ISO     fructosamine catabolic process GO:0030392 ISS     response to estradiol GO:0032355 IEP     response to retinoic acid GO:0032526 IEP     maintenance of lens transparency GO:0036438 IMP     retinol metabolic process GO:0042572 IEA     retinol metabolic process GO:0042572 ISO     retinoic acid metabolic process GO:0042573 ISO     9-cis-retinoic acid biosynthetic process GO:0042904 IEA     9-cis-retinoic acid biosynthetic process GO:0042904 ISO     9-cis-retinoic acid metabolic process GO:0042905 IDA     positive regulation of apoptotic process GO:0043065 IEA     positive regulation of apoptotic process GO:0043065 ISO     estrous cycle GO:0044849 IEP     response to ethanol GO:0045471 IDA     embryonic eye morphogenesis GO:0048048 ISO     cellular detoxification of aldehyde GO:0110095 IMP     cellular detoxification of aldehyde GO:0110095 ISO     negative regulation of cold-induced thermogenesis GO:0120163 IEA     negative regulation of cold-induced thermogenesis GO:0120163 ISO     negative regulation of cold-induced thermogenesis GO:0120163 ISS Subcellular Localization     cytoplasm GO:0005737 IEA     cytosol GO:0005829 ISO     cytosol GO:0005829 ISS     axon GO:0030424 IEA     axon GO:0030424 ISO     axon GO:0030424 ISS     synapse GO:0045202 IEA     synapse GO:0045202 ISO     synapse GO:0045202 ISS