Gene description for Akr1b1
Gene name	aldo-keto reductase family 1, member B1 (aldose reductase)
Gene symbol	Akr1b1
Other names/aliases	ALDRED ALR-P-I Akr1b3 Akr1b4 Aldr1 Alr RATALDRED
Species	Rattus norvegicus
Database cross references - Akr1b1
ExoCarta	ExoCarta_24192
Vesiclepedia	VP_24192
Entrez Gene	24192
UniProt	P07943
Akr1b1 identified in sEVs derived from the following tissue/cell type
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046

Gene ontology annotations for Akr1b1

Molecular Function     retinal dehydrogenase activity GO:0001758 ISO     retinal dehydrogenase activity GO:0001758 ISS     aldose reductase (NADPH) activity GO:0004032 IBA     aldose reductase (NADPH) activity GO:0004032 IDA     aldose reductase (NADPH) activity GO:0004032 ISO     oxidoreductase activity GO:0016491 IEA     cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase activity GO:0018505 IDA     prostaglandin H2 endoperoxidase reductase activity GO:0036130 IEA     glyceraldehyde oxidoreductase activity GO:0043795 ISO     allyl-alcohol dehydrogenase activity GO:0047655 IEA     L-glucuronate reductase activity GO:0047939 ISO     glycerol dehydrogenase (NADP+) activity GO:0047956 IEA     all-trans-retinol dehydrogenase (NADP+) activity GO:0052650 IEA Biological Process     retinoid metabolic process GO:0001523 ISO     retinoid metabolic process GO:0001523 ISS     tissue homeostasis GO:0001894 IMP     epithelial cell maturation GO:0002070 ISO     renal water homeostasis GO:0003091 ISO     monosaccharide metabolic process GO:0005996 IDA     sorbitol biosynthetic process GO:0006061 IMP     lipid metabolic process GO:0006629 IEA     prostaglandin metabolic process GO:0006693 IEA     L-ascorbic acid biosynthetic process GO:0019853 ISO     stress-activated protein kinase signaling cascade GO:0031098 IMP     regulation of urine volume GO:0035809 ISO     norepinephrine metabolic process GO:0042415 IDA     retinol metabolic process GO:0042572 IEA     negative regulation of apoptotic process GO:0043066 ISO     daunorubicin metabolic process GO:0044597 ISO     doxorubicin metabolic process GO:0044598 ISO     fructose biosynthetic process GO:0046370 ISO     positive regulation of receptor signaling pathway via JAK-STAT GO:0046427 IMP     positive regulation of smooth muscle cell proliferation GO:0048661 IMP     maternal process involved in female pregnancy GO:0060135 IEP     cellular hyperosmotic salinity response GO:0071475 ISO     inner medullary collecting duct development GO:0072061 IDA     metanephric collecting duct development GO:0072205 ISO     response to thyroid hormone GO:0097066 IEP     cellular response to methylglyoxal GO:0097238 IDA     cellular response to peptide GO:1901653 IEP Subcellular Localization     extracellular space GO:0005615 IDA     nucleoplasm GO:0005654 ISO     mitochondrion GO:0005739 ISO     cytosol GO:0005829 IBA     cytosol GO:0005829 ISO     cytosol GO:0005829 ISO     plasma membrane bounded cell projection cytoplasm GO:0032838 IDA     paranodal junction GO:0033010 IDA     mast cell granule GO:0042629 IDA     Schmidt-Lanterman incisure GO:0043220 IDA     perinuclear region of cytoplasm GO:0048471 IDA     Schwann cell microvillus GO:0097454 IDA