Gene description for Akr1b1
Gene name	aldo-keto reductase family 1, member B1 (aldose reductase)
Gene symbol	Akr1b1
Other names/aliases	ALDRED ALR-P-I Akr1b3 Akr1b4 Aldr1 Alr RATALDRED
Species	Rattus norvegicus
Database cross references - Akr1b1
ExoCarta	ExoCarta_24192
Entrez Gene	24192
UniProt	P07943
Akr1b1 identified in exosomes derived from the following tissue/cell type
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046

Gene ontology annotations for Akr1b1

Molecular Function     alditol:NADP+ 1-oxidoreductase activity GO:0004032 ISO     glyceraldehyde oxidoreductase activity GO:0043795 ISO Biological Process     doxorubicin metabolic process GO:0044598 ISO     cellular response to methylglyoxal GO:0097238 IDA     cellular response to hydrogen peroxide GO:0070301 IDA     daunorubicin metabolic process GO:0044597 ISO     positive regulation of JAK-STAT cascade GO:0046427 IMP     oxidation-reduction process GO:0055114 IEA     tissue homeostasis GO:0001894 IMP     response to organic substance GO:0010033 IDA     norepinephrine metabolic process GO:0042415 IDA     cellular response to peptide GO:1901653 IEP     stress-activated protein kinase signaling cascade GO:0031098 IMP     monosaccharide metabolic process GO:0005996 IDA     sorbitol biosynthetic process GO:0006061 IMP     response to thyroid hormone GO:0097066 IEP     maternal process involved in female pregnancy GO:0060135 IEP     inner medullary collecting duct development GO:0072061 IDA     naphthalene metabolic process GO:0018931 IDA     positive regulation of smooth muscle cell proliferation GO:0048661 IMP     response to water deprivation GO:0009414 IDA Subcellular Localization     cytoplasm GO:0005737 ISO     nucleoplasm GO:0005654 ISO     extracellular exosome GO:0070062 ISO     perinuclear region of cytoplasm GO:0048471 IDA     cytosol GO:0005829 IDA     Schmidt-Lanterman incisure GO:0043220 IDA     mast cell granule GO:0042629 IDA     Schwann cell microvillus GO:0097454 IDA     extracellular space GO:0005615 IDA     paranodal junction GO:0033010 IDA     cell projection cytoplasm GO:0032838 IDA