Gene description for Impad1
Gene name inositol monophosphatase domain containing 1
Gene symbol Impad1
Other names/aliases 1110001C20Rik
AA408880
AI451589
AL022796
B230207P20
Jaws
gPAPP
Species Mus musculus
 Database cross references - Impad1
ExoCarta ExoCarta_242291
Entrez Gene 242291
UniProt Q80V26  
 Impad1 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Impad1
Molecular Function
    3'(2'),5'-bisphosphate nucleotidase activity GO:0008441 IEA
    inositol monophosphate 4-phosphatase activity GO:0052833 IEA
    inositol monophosphate 3-phosphatase activity GO:0052832 IEA
    inositol monophosphate 1-phosphatase activity GO:0008934 IEA
    3'-nucleotidase activity GO:0008254 IDA
    hydrolase activity GO:0016787 IEA
    metal ion binding GO:0046872 IEA
    inositol monophosphate phosphatase activity GO:0052834 IEA
Biological Process
    chondrocyte development GO:0002063 IMP
    chondroitin sulfate metabolic process GO:0030204 IMP
    endochondral ossification GO:0001958 IMP
    skeletal system development GO:0001501 IMP
    post-embryonic development GO:0009791 IMP
    dephosphorylation GO:0016311 IDA
    embryonic digit morphogenesis GO:0042733 IMP
    phosphatidylinositol phosphorylation GO:0046854 IEA
Subcellular Localization
    integral component of membrane GO:0016021 IEA
    Golgi apparatus GO:0005794 ISO
    membrane GO:0016020 ISO
 Experiment description of studies that identified Impad1 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Impad1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Impad1 is involved
No pathways found





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