Gene description for Bnc2
Gene name basonuclin 2
Gene symbol Bnc2
Other names/aliases 5031434M05Rik
8430420F16Rik
Species Mus musculus
 Database cross references - Bnc2
ExoCarta ExoCarta_242509
Entrez Gene 242509
UniProt Q8BMQ3  
 Bnc2 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Bnc2
Molecular Function
    DNA binding GO:0003677 IDA
    metal ion binding GO:0046872 IEA
Biological Process
    regulation of apoptotic process GO:0042981 IMP
    transcription, DNA-templated GO:0006351 IEA
    tongue development GO:0043586 IMP
    endochondral bone growth GO:0003416 IMP
    mesenchyme development GO:0060485 IMP
    palate development GO:0060021 IMP
    regulation of transcription, DNA-templated GO:0006355 IEA
Subcellular Localization
    cytoplasm GO:0005737 ISO
    plasma membrane GO:0005886 ISO
    nucleus GO:0005634 ISO
    nucleoplasm GO:0005654 ISO
 Experiment description of studies that identified Bnc2 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Bnc2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Bnc2 is involved
No pathways found





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