Gene description for Bnc2
Gene name basonuclin 2
Gene symbol Bnc2
Other names/aliases 5031434M05Rik
8430420F16Rik
Species Mus musculus
 Database cross references - Bnc2
ExoCarta ExoCarta_242509
Vesiclepedia VP_242509
Entrez Gene 242509
UniProt Q8BMQ3  
 Bnc2 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Bnc2
Molecular Function
    rDNA binding GO:0000182 IDA
    DNA binding GO:0003677 IDA
    metal ion binding GO:0046872 IEA
Biological Process
    endochondral bone growth GO:0003416 IMP
    regulation of DNA-templated transcription GO:0006355 IBA
    regulation of apoptotic process GO:0042981 IMP
    tongue development GO:0043586 IMP
    roof of mouth development GO:0060021 IMP
    mesenchyme development GO:0060485 IMP
Subcellular Localization
    chromatin GO:0000785 IDA
    nucleus GO:0005634 IBA
    nucleus GO:0005634 IDA
    nucleoplasm GO:0005654 IEA
    nucleoplasm GO:0005654 ISO
 Experiment description of studies that identified Bnc2 in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Bnc2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Nanog  
Affinity Capture-MS Mus musculus
View the network image/svg+xml
 Pathways in which Bnc2 is involved
No pathways found





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