Gene description for Cp
Gene name ceruloplasmin (ferroxidase)
Gene symbol Cp
Other names/aliases CERP
Species Rattus norvegicus
 Database cross references - Cp
ExoCarta ExoCarta_24268
Entrez Gene 24268
 Cp identified in exosomes derived from the following tissue/cell type
Cortical neurones 16446100    
 Gene ontology annotations for Cp
Molecular Function
    copper ion binding GO:0005507 TAS
    ferroxidase activity GO:0004322 TAS
    chaperone binding GO:0051087 ISO
Biological Process
    aging GO:0007568 IEP
    response to copper ion GO:0046688 IDA
    lung development GO:0030324 IEP
    plasma membrane copper ion transport GO:0015679 TAS
    oxidation-reduction process GO:0055114 ISO
    response to nutrient GO:0007584 IEP
    liver development GO:0001889 IEP
    cellular iron ion homeostasis GO:0006879 TAS
Subcellular Localization
    anchored component of plasma membrane GO:0046658 IDA
    blood microparticle GO:0072562 ISO
    lysosomal membrane GO:0005765 ISO
    extracellular space GO:0005615 ISO
    extracellular exosome GO:0070062 ISO
 Experiment description of studies that identified Cp in exosomes
1
Experiment ID 30
ISEV standards
EM
EV Biophysical techniques
Alix|TSG101
EV Cytosolic markers
FLOT
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 16446100    
Organism Rattus norvegicus
Experiment description Exosomes are released by cultured cortical neurones.
Authors Faure J, Lachenal G, Court M, Hirrlinger J, Chatellard-Causse C, Blot B, Grange J, Schoehn G, Goldberg Y, Boyer V, Kirchhoff F, Raposo G, Garin J, Sadoul R
Journal name MCN
Publication year 2006
Sample Cortical neurones
Sample name Cortical neurones
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.13 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
 Protein-protein interactions for Cp
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Cp is involved
No pathways found





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