Gene description for Cyp4b1
Gene name cytochrome P450, family 4, subfamily b, polypeptide 1
Gene symbol Cyp4b1
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Cyp4b1
ExoCarta ExoCarta_24307
Entrez Gene 24307
UniProt P15129  
 Cyp4b1 identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Cyp4b1
Molecular Function
    heme binding GO:0020037 IEA
    iron ion binding GO:0005506 IEA
    drug binding GO:0008144 IMP
    aromatase activity GO:0070330 IEA
    oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen GO:0016705 IEA
    monooxygenase activity GO:0004497 TAS
    fluorene oxygenase activity GO:0018585 IDA
Biological Process
    cellular aromatic compound metabolic process GO:0006725 IMP
    oxidation-reduction process GO:0055114 IEA
    exogenous drug catabolic process GO:0042738 IMP
    fluorene metabolic process GO:0018917 IDA
    biphenyl metabolic process GO:0018879 IMP
Subcellular Localization
    endoplasmic reticulum membrane GO:0005789 IEA
    intracellular membrane-bounded organelle GO:0043231 IDA
 Experiment description of studies that identified Cyp4b1 in exosomes
1
Experiment ID 225
ISEV standards
EM
EV Biophysical techniques
GAPDH
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Cyp4b1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Cyp4b1 is involved
PathwayEvidenceSource
Fatty acids IEA Reactome





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