Gene description for Fbp1
Gene name	fructose-1,6-bisphosphatase 1
Gene symbol	Fbp1
Other names/aliases	Fdp
Species	Rattus norvegicus
Database cross references - Fbp1
ExoCarta	ExoCarta_24362
Vesiclepedia	VP_24362
Entrez Gene	24362
UniProt	P19112
Fbp1 identified in sEVs derived from the following tissue/cell type
Hepatocytes	19367702
Urine	20535238

Gene ontology annotations for Fbp1

Molecular Function     AMP binding GO:0016208 IEA     AMP binding GO:0016208 ISO     AMP binding GO:0016208 ISS     fructose 1,6-bisphosphate 1-phosphatase activity GO:0042132 IBA     fructose 1,6-bisphosphate 1-phosphatase activity GO:0042132 IDA     fructose 1,6-bisphosphate 1-phosphatase activity GO:0042132 IEA     fructose 1,6-bisphosphate 1-phosphatase activity GO:0042132 ISO     fructose 1,6-bisphosphate 1-phosphatase activity GO:0042132 TAS     identical protein binding GO:0042802 IEA     identical protein binding GO:0042802 ISO     identical protein binding GO:0042802 ISS     metal ion binding GO:0046872 IEA     metal ion binding GO:0046872 ISO     metal ion binding GO:0046872 ISS     monosaccharide binding GO:0048029 IDA     RNA polymerase II-specific DNA-binding transcription factor binding GO:0061629 IEA     RNA polymerase II-specific DNA-binding transcription factor binding GO:0061629 ISO Biological Process     negative regulation of transcription by RNA polymerase II GO:0000122 IEA     negative regulation of transcription by RNA polymerase II GO:0000122 ISO     fructose metabolic process GO:0006000 IBA     fructose 6-phosphate metabolic process GO:0006002 IBA     fructose 6-phosphate metabolic process GO:0006002 IDA     fructose 6-phosphate metabolic process GO:0006002 IEA     fructose 6-phosphate metabolic process GO:0006002 ISO     fructose 6-phosphate metabolic process GO:0006002 ISS     gluconeogenesis GO:0006094 IBA     gluconeogenesis GO:0006094 IDA     gluconeogenesis GO:0006094 IEA     gluconeogenesis GO:0006094 ISO     regulation of gluconeogenesis GO:0006111 IEA     regulation of gluconeogenesis GO:0006111 ISO     regulation of gluconeogenesis GO:0006111 ISS     dephosphorylation GO:0016311 ISO     dephosphorylation GO:0016311 ISS     negative regulation of cell growth GO:0030308 IEA     negative regulation of cell growth GO:0030308 ISO     negative regulation of cell growth GO:0030308 ISS     fructose 1,6-bisphosphate metabolic process GO:0030388 IBA     response to nutrient levels GO:0031667 IEP     cellular response to insulin stimulus GO:0032869 IEP     negative regulation of glycolytic process GO:0045820 IEA     negative regulation of glycolytic process GO:0045820 ISO     negative regulation of glycolytic process GO:0045820 ISS     negative regulation of Ras protein signal transduction GO:0046580 IEA     negative regulation of Ras protein signal transduction GO:0046580 ISO     negative regulation of Ras protein signal transduction GO:0046580 ISS     cellular response to magnesium ion GO:0071286 IEA     cellular response to magnesium ion GO:0071286 ISO     cellular response to magnesium ion GO:0071286 ISS     cellular response to cAMP GO:0071320 IEP     cellular response to xenobiotic stimulus GO:0071466 IEA     cellular response to xenobiotic stimulus GO:0071466 ISO     cellular response to xenobiotic stimulus GO:0071466 ISS     cellular hyperosmotic salinity response GO:0071475 IEP     cellular hypotonic salinity response GO:0071477 IEP     cellular response to raffinose GO:0097403 IEP     cellular response to phorbol 13-acetate 12-myristate GO:1904628 IEP Subcellular Localization     extracellular space GO:0005615 IDA     nucleus GO:0005634 IEA     nucleus GO:0005634 ISO     cytoplasm GO:0005737 IBA     cytoplasm GO:0005737 IEA     cytoplasm GO:0005737 ISO     cytoplasm GO:0005737 ISS     cytosol GO:0005829 IBA