Gene description for Fh
Gene name	fumarate hydratase
Gene symbol	Fh
Other names/aliases	Fh1
Species	Rattus norvegicus
Database cross references - Fh
ExoCarta	ExoCarta_24368
Vesiclepedia	VP_24368
Entrez Gene	24368
Fh identified in sEVs derived from the following tissue/cell type
Adipocytes	25998041

Gene ontology annotations for Fh

Molecular Function     fumarate hydratase activity GO:0004333 IBA     fumarate hydratase activity GO:0004333 IMP     fumarate hydratase activity GO:0004333 ISO     fumarate hydratase activity GO:0004333 ISS     histone binding GO:0042393 ISO Biological Process     urea cycle GO:0000050 ISO     urea cycle GO:0000050 ISS     regulation of arginine metabolic process GO:0000821 ISO     regulation of arginine metabolic process GO:0000821 ISS     tricarboxylic acid cycle GO:0006099 IBA     tricarboxylic acid cycle GO:0006099 IEA     tricarboxylic acid cycle GO:0006099 ISO     fumarate metabolic process GO:0006106 IBA     fumarate metabolic process GO:0006106 ISO     fumarate metabolic process GO:0006106 ISS     fumarate metabolic process GO:0006106 TAS     malate metabolic process GO:0006108 IBA     malate metabolic process GO:0006108 ISO     DNA repair GO:0006281 IEA     arginine metabolic process GO:0006525 IEA     DNA damage response GO:0006974 ISO     DNA damage response GO:0006974 ISS     homeostasis of number of cells within a tissue GO:0048873 ISO     positive regulation of cold-induced thermogenesis GO:0120162 ISO     positive regulation of cold-induced thermogenesis GO:0120162 ISS     positive regulation of double-strand break repair via nonhomologous end joining GO:2001034 ISO     positive regulation of double-strand break repair via nonhomologous end joining GO:2001034 ISS Subcellular Localization     nucleus GO:0005634 IEA     nucleus GO:0005634 ISO     chromosome GO:0005694 IEA     cytoplasm GO:0005737 ISO     mitochondrion GO:0005739 IBA     mitochondrion GO:0005739 ISO     mitochondrial matrix GO:0005759 ISO     cytosol GO:0005829 IEA     cytosol GO:0005829 ISO     site of double-strand break GO:0035861 ISO