Gene description for Fh
Gene name fumarate hydratase
Gene symbol Fh
Other names/aliases Fh1
Species Rattus norvegicus
 Database cross references - Fh
ExoCarta ExoCarta_24368
Entrez Gene 24368
 Fh identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Fh
Molecular Function
    fumarate hydratase activity GO:0004333 ISO
Biological Process
    tricarboxylic acid cycle GO:0006099 IEA
    fumarate metabolic process GO:0006106 TAS
    homeostasis of number of cells within a tissue GO:0048873 ISO
    malate metabolic process GO:0006108 IDA
Subcellular Localization
    mitochondrion GO:0005739 ISO
    extracellular exosome GO:0070062 ISO
    tricarboxylic acid cycle enzyme complex GO:0045239 IEA
 Experiment description of studies that identified Fh in exosomes
1
Experiment ID 225
ISEV standards
EM
EV Biophysical techniques
GAPDH
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Fh
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Fh is involved
No pathways found





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