Gene description for Grin1
Gene name	glutamate receptor, ionotropic, N-methyl D-aspartate 1
Gene symbol	Grin1
Other names/aliases	GluN1 NMDAR1 NR1
Species	Rattus norvegicus
Database cross references - Grin1
ExoCarta	ExoCarta_24408
Entrez Gene	24408
UniProt	P35439
Grin1 identified in exosomes derived from the following tissue/cell type
Cortical neurones	16446100

Gene ontology annotations for Grin1

Molecular Function     protein binding GO:0005515 IPI     N-methyl-D-aspartate selective glutamate receptor activity GO:0004972 TAS     extracellular-glutamate-gated ion channel activity GO:0005234 IBA     receptor binding GO:0005102 ISO     glycine binding GO:0016594 ISO     calmodulin binding GO:0005516 ISO     enzyme binding GO:0019899 IPI     protein dimerization activity GO:0046983 IDA     voltage-gated cation channel activity GO:0022843 IMP     protein heterodimerization activity GO:0046982 IDA     glutamate receptor binding GO:0035254 IPI     calcium ion binding GO:0005509 ISO     neurotransmitter binding GO:0042165 IDA     ionotropic glutamate receptor activity GO:0004970 TAS     glutamate binding GO:0016595 ISO     calcium channel activity GO:0005262 ISO     cation channel activity GO:0005261 ISO Biological Process     regulation of synapse assembly GO:0051963 ISO     ion transmembrane transport GO:0034220 ISO     regulation of ion transmembrane transport GO:0034765 IMP     long-term memory GO:0007616 ISO     cation transport GO:0006812 ISO     response to amphetamine GO:0001975 ISO     cellular calcium ion homeostasis GO:0006874 ISO     learning or memory GO:0007611 TAS     social behavior GO:0035176 ISO     respiratory gaseous exchange GO:0007585 ISO     olfactory learning GO:0008355 ISO     male mating behavior GO:0060179 ISO     regulation of membrane potential GO:0042391 ISO     cerebral cortex development GO:0021987 ISO     regulation of neuronal synaptic plasticity GO:0048168 ISO     ionotropic glutamate receptor signaling pathway GO:0035235 ISO     regulation of respiratory gaseous exchange GO:0043576 ISO     neuromuscular process GO:0050905 ISO     associative learning GO:0008306 ISO     response to morphine GO:0043278 ISO     regulation of cell communication GO:0010646 ISO     visual learning GO:0008542 ISO     positive regulation of cell death GO:0010942 IDA     conditioned taste aversion GO:0001661 ISO     regulation of neuron apoptotic process GO:0043523 ISO     positive regulation of excitatory postsynaptic membrane potential GO:2000463 IDA     sensory perception of pain GO:0019233 ISO     calcium ion transport GO:0006816 ISO     positive regulation of apoptotic process GO:0043065 ISO     rhythmic process GO:0048511 IDA     positive regulation of transcription from RNA polymerase II promoter GO:0045944 ISO     response to ethanol GO:0045471 ISO     negative regulation of neuron apoptotic process GO:0043524 ISO     regulation of axonogenesis GO:0050770 ISO     response to organic cyclic compound GO:0014070 IEP     response to calcium ion GO:0051592 IEP     regulation of synaptic plasticity GO:0048167 ISO     synaptic transmission, glutamatergic GO:0035249 ISO     cellular response to manganese ion GO:0071287 IEP     calcium ion homeostasis GO:0055074 ISO     response to amine GO:0014075 IEP     suckling behavior GO:0001967 ISO     propylene metabolic process GO:0018964 ISO     memory GO:0007613 ISO     pons maturation GO:0021586 ISO     protein tetramerization GO:0051262 IDA     startle response GO:0001964 ISO     adult locomotory behavior GO:0008344 ISO     regulation of dendrite morphogenesis GO:0048814 ISO     response to fungicide GO:0060992 IEP     prepulse inhibition GO:0060134 ISO     regulation of excitatory postsynaptic membrane potential GO:0060079 ISO     learning GO:0007612 ISO     calcium ion transmembrane transport GO:0070588 ISO     regulation of long-term neuronal synaptic plasticity GO:0048169 ISO Subcellular Localization     dendrite membrane GO:0032590 IDA     postsynaptic membrane GO:0045211 ISO     postsynaptic density GO:0014069 ISO     cell junction GO:0030054 IEA     membrane GO:0016020 ISO     dendritic branch GO:0044307 IDA     integral component of plasma membrane GO:0005887 ISO     dendrite GO:0030425 ISO     cell GO:0005623 ISO     endoplasmic reticulum GO:0005783 ISO     cell surface GO:0009986 ISO     excitatory synapse GO:0060076 IDA     dendritic spine GO:0043197 ISO     synapse GO:0045202 ISO     synaptic cleft GO:0043083 IDA     synaptic vesicle GO:0008021 ISO     plasma membrane GO:0005886 IBA     N-methyl-D-aspartate selective glutamate receptor complex GO:0017146 TAS     cytoplasm GO:0005737 ISO     neuronal cell body GO:0043025 IDA     neuronal postsynaptic density GO:0097481 ISO     terminal bouton GO:0043195 IDA