Gene description for Gsta2
Gene name glutathione S-transferase alpha 2
Gene symbol Gsta2
Other names/aliases Gsta1
Species Rattus norvegicus
 Database cross references - Gsta2
ExoCarta ExoCarta_24422
Vesiclepedia VP_24422
Entrez Gene 24422
UniProt P00502  
 Gsta2 identified in exosomes derived from the following tissue/cell type
Urine 20535238    
 Gene ontology annotations for Gsta2
Molecular Function
    glutathione transferase activity GO:0004364 IBA
    glutathione transferase activity GO:0004364 IDA
    glutathione transferase activity GO:0004364 IEA
    glutathione transferase activity GO:0004364 ISO
    steroid delta-isomerase activity GO:0004769 ISS
    dinitrosyl-iron complex binding GO:0035731 IPI
    protein homodimerization activity GO:0042803 IDA
    glutathione binding GO:0043295 IDA
Biological Process
    prostaglandin metabolic process GO:0006693 ISS
    glutathione metabolic process GO:0006749 IBA
    xenobiotic metabolic process GO:0006805 IBA
    response to bacterium GO:0009617 ISO
    epithelial cell differentiation GO:0030855 ISO
    response to stilbenoid GO:0035634 ISO
    xenobiotic catabolic process GO:0042178 IDA
    cellular oxidant detoxification GO:0098869 IEA
    glutathione derivative biosynthetic process GO:1901687 ISS
Subcellular Localization
    cytoplasm GO:0005737 IEA
    mitochondrion GO:0005739 ISO
    cytosol GO:0005829 IBA
    cytosol GO:0005829 IDA
    cytosol GO:0005829 ISO
 Experiment description of studies that identified Gsta2 in exosomes
1
Experiment ID 192
MISEV standards
CEM
Biophysical techniques
TSG101|HSP70|CD63|CD81|FLOT
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20535238    
Organism Rattus norvegicus
Experiment description Candidate biomarkers in exosome-like vesicles purified from rat and mouse urine samples.
Authors "Conde-Vancells J, Rodriguez-Suarez E, Gonzalez E, Berisa A, Gil D, Embade N, Valle M, Luka Z, Elortza F, Wagner C, Lu SC, Mato JM, Falcon-Perez M."
Journal name Proteomics Clin Appl
Publication year 2010
Sample Urine
Sample name Urine - Rats of liver injury
Isolation/purification methods Differential centrifugation
Filtration
UltracentrifugationSucrose cushion
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Gsta2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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