Gene description for Hprt1
Gene name	hypoxanthine phosphoribosyltransferase 1
Gene symbol	Hprt1
Other names/aliases	Hgprtase Hprt
Species	Rattus norvegicus
Database cross references - Hprt1
ExoCarta	ExoCarta_24465
Vesiclepedia	VP_24465
Entrez Gene	24465
UniProt	P27605
Hprt1 identified in sEVs derived from the following tissue/cell type
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046

Gene ontology annotations for Hprt1

Molecular Function     nucleotide binding GO:0000166 IEA     magnesium ion binding GO:0000287 IBA     magnesium ion binding GO:0000287 IEA     magnesium ion binding GO:0000287 ISO     hypoxanthine phosphoribosyltransferase activity GO:0004422 IBA     hypoxanthine phosphoribosyltransferase activity GO:0004422 IDA     hypoxanthine phosphoribosyltransferase activity GO:0004422 IEA     hypoxanthine phosphoribosyltransferase activity GO:0004422 ISO     identical protein binding GO:0042802 IEA     identical protein binding GO:0042802 ISO     metal ion binding GO:0046872 IEA     guanine phosphoribosyltransferase activity GO:0052657 IEA     guanine phosphoribosyltransferase activity GO:0052657 ISO     guanine phosphoribosyltransferase activity GO:0052657 ISS Biological Process     T cell mediated cytotoxicity GO:0001913 IEA     T cell mediated cytotoxicity GO:0001913 ISO     response to amphetamine GO:0001975 IEA     response to amphetamine GO:0001975 ISO     purine nucleotide biosynthetic process GO:0006164 ISO     purine ribonucleoside salvage GO:0006166 IEA     purine ribonucleoside salvage GO:0006166 ISO     purine ribonucleoside salvage GO:0006166 ISO     guanine salvage GO:0006178 IBA     guanine salvage GO:0006178 IEA     guanine salvage GO:0006178 ISO     guanine salvage GO:0006178 ISS     spermatogenesis GO:0007283 IEP     grooming behavior GO:0007625 IEA     grooming behavior GO:0007625 ISO     grooming behavior GO:0007625 ISO     locomotory behavior GO:0007626 IEA     locomotory behavior GO:0007626 ISO     striatum development GO:0021756 IEA     striatum development GO:0021756 ISO     cerebral cortex neuron differentiation GO:0021895 IEA     cerebral cortex neuron differentiation GO:0021895 ISO     central nervous system neuron development GO:0021954 IEA     central nervous system neuron development GO:0021954 ISO     GMP salvage GO:0032263 IBA     GMP salvage GO:0032263 IEA     GMP salvage GO:0032263 ISO     GMP salvage GO:0032263 ISO     IMP salvage GO:0032264 IBA     IMP salvage GO:0032264 IEA     IMP salvage GO:0032264 ISO     cellular response to insulin stimulus GO:0032869 IEP     dopamine metabolic process GO:0042417 IEA     dopamine metabolic process GO:0042417 ISO     hypoxanthine salvage GO:0043103 IEA     hypoxanthine salvage GO:0043103 ISO     hypoxanthine salvage GO:0043103 ISS     AMP salvage GO:0044209 IEA     AMP salvage GO:0044209 ISO     positive regulation of dopamine metabolic process GO:0045964 IEA     positive regulation of dopamine metabolic process GO:0045964 ISO     GMP catabolic process GO:0046038 IEA     GMP catabolic process GO:0046038 ISO     GMP catabolic process GO:0046038 ISS     IMP metabolic process GO:0046040 ISO     IMP metabolic process GO:0046040 ISS     adenine metabolic process GO:0046083 IEA     adenine metabolic process GO:0046083 ISO     hypoxanthine metabolic process GO:0046100 IBA     hypoxanthine metabolic process GO:0046100 IDA     hypoxanthine metabolic process GO:0046100 ISO     hypoxanthine metabolic process GO:0046100 ISO     lymphocyte proliferation GO:0046651 IEA     lymphocyte proliferation GO:0046651 ISO     dendrite morphogenesis GO:0048813 IEA     dendrite morphogenesis GO:0048813 ISO     protein homotetramerization GO:0051289 IEA     protein homotetramerization GO:0051289 ISO     dopaminergic neuron differentiation GO:0071542 IEA     dopaminergic neuron differentiation GO:0071542 ISO Subcellular Localization     cytoplasm GO:0005737 IEA     cytoplasm GO:0005737 ISO     cytosol GO:0005829 IBA     cytosol GO:0005829 IEA     cytosol GO:0005829 ISO     cytosol GO:0005829 ISO