Gene description for Hsd3b5
Gene name	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5
Gene symbol	Hsd3b5
Other names/aliases	Hsd1 Hsd3b RATHSDI
Species	Rattus norvegicus
Database cross references - Hsd3b5
ExoCarta	ExoCarta_24470
Vesiclepedia	VP_24470
Entrez Gene	24470
UniProt	P27364
Hsd3b5 identified in sEVs derived from the following tissue/cell type
Hepatocytes	19367702

Gene ontology annotations for Hsd3b5

Molecular Function     3-keto sterol reductase activity GO:0000253 IEA     3-beta-hydroxy-delta5-steroid dehydrogenase (NAD+) activity GO:0003854 IDA     steroid binding GO:0005496 IDA     steroid dehydrogenase activity GO:0016229 TAS     oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0016616 IBA     oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0016616 IEA     5alpha-androstane-3beta,17beta-diol dehydrogenase activity GO:0047024 IEA Biological Process     steroid biosynthetic process GO:0006694 IBA     steroid biosynthetic process GO:0006694 IDA     steroid biosynthetic process GO:0006694 IEA     steroid biosynthetic process GO:0006694 TAS     C21-steroid hormone metabolic process GO:0008207 IBA     progesterone metabolic process GO:0042448 IDA     regulation of steroid biosynthetic process GO:0050810 IDA Subcellular Localization     cytoplasm GO:0005737 IBA     endoplasmic reticulum membrane GO:0005789 IEA     mitochondrial membrane GO:0031966 IEA     intracellular membrane-bounded organelle GO:0043231 IBA