Gene description for Igf2
Gene name	insulin-like growth factor 2
Gene symbol	Igf2
Other names/aliases	IGFII RNIGF2
Species	Rattus norvegicus
Database cross references - Igf2
ExoCarta	ExoCarta_24483
Entrez Gene	24483
UniProt	P01346
Igf2 identified in exosomes derived from the following tissue/cell type
Pancreatic cancer cells	20124479
Pancreatic cancer cells	20124479

Gene ontology annotations for Igf2

Molecular Function     insulin-like growth factor receptor binding GO:0005159 ISO     growth factor activity GO:0008083 TAS     insulin receptor binding GO:0005158 ISO     receptor activator activity GO:0030546 ISO     hormone activity GO:0005179 IEA     protein serine/threonine kinase activator activity GO:0043539 ISO     protein binding GO:0005515 IPI Biological Process     positive regulation of steroid hormone biosynthetic process GO:0090031 IDA     response to estradiol GO:0032355 IEP     cell proliferation GO:0008283 TAS     positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 ISO     insulin receptor signaling pathway via phosphatidylinositol 3-kinase GO:0038028 ISO     positive regulation of insulin receptor signaling pathway GO:0046628 ISO     response to drug GO:0042493 IDA     female pregnancy GO:0007565 IEP     positive regulation of transcription from RNA polymerase II promoter GO:0045944 ISO     positive regulation of MAPK cascade GO:0043410 ISO     positive regulation of protein serine/threonine kinase activity GO:0071902 ISO     positive regulation of glycogen biosynthetic process GO:0045725 ISO     glucose metabolic process GO:0006006 IEA     negative regulation of natural killer cell mediated cytotoxicity GO:0045953 IDA     positive regulation of glycogen (starch) synthase activity GO:2000467 ISO     cellular response to mechanical stimulus GO:0071260 IEP     positive regulation of protein kinase B signaling GO:0051897 ISO     positive regulation of receptor activity GO:2000273 ISO     response to radiation GO:0009314 IEP     exocrine pancreas development GO:0031017 ISO     response to nutrient levels GO:0031667 IEP     positive regulation of catalytic activity GO:0043085 ISO     osteoblast differentiation GO:0001649 IEA     wound healing GO:0042060 IEP     organ morphogenesis GO:0009887 ISO     memory GO:0007613 IMP     striated muscle cell differentiation GO:0051146 ISO     response to nicotine GO:0035094 IEP     positive regulation of activated T cell proliferation GO:0042104 ISO     response to ethanol GO:0045471 IEP     positive regulation of protein phosphorylation GO:0001934 ISO     response to organic cyclic compound GO:0014070 IDA     positive regulation of mitotic nuclear division GO:0045840 ISO Subcellular Localization     extracellular exosome GO:0070062 ISO     extracellular space GO:0005615 TAS