Gene description for Ivd
Gene name isovaleryl-CoA dehydrogenase
Gene symbol Ivd
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Ivd
ExoCarta ExoCarta_24513
Entrez Gene 24513
UniProt P12007  
 Ivd identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Ivd
Molecular Function
    flavin adenine dinucleotide binding GO:0050660 IEA
    isovaleryl-CoA dehydrogenase activity GO:0008470 ISO
Biological Process
    leucine catabolic process GO:0006552 IEA
    fatty acid beta-oxidation using acyl-CoA dehydrogenase GO:0033539 IC
    leucine metabolic process GO:0006551 TAS
    protein homooligomerization GO:0051260 TAS
Subcellular Localization
    mitochondrial matrix GO:0005759 IDA
    mitochondrial membrane GO:0031966 IDA
    mitochondrion GO:0005739 ISO
    nucleoplasm GO:0005654 ISO
 Experiment description of studies that identified Ivd in exosomes
1
Experiment ID 225
ISEV standards
✔
EM
EV Biophysical techniques
✔
GAPDH
EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Ivd
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Ivd is involved
PathwayEvidenceSource
Branched-chain amino acid catabolism IEA Reactome





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