Gene description for Ivd
Gene name isovaleryl-CoA dehydrogenase
Gene symbol Ivd
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Ivd
ExoCarta ExoCarta_24513
Vesiclepedia VP_24513
Entrez Gene 24513
UniProt P12007  
 Ivd identified in sEVs derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Ivd
Molecular Function
    acyl-CoA dehydrogenase activity GO:0003995 IEA
    3-methylbutanoyl-CoA dehydrogenase activity GO:0008470 IBA
    3-methylbutanoyl-CoA dehydrogenase activity GO:0008470 IDA
    3-methylbutanoyl-CoA dehydrogenase activity GO:0008470 ISO
    short-chain fatty acyl-CoA dehydrogenase activity GO:0016937 IEA
    identical protein binding GO:0042802 IPI
    flavin adenine dinucleotide binding GO:0050660 IEA
Biological Process
    L-leucine metabolic process GO:0006551 TAS
    L-leucine catabolic process GO:0006552 IBA
    L-leucine catabolic process GO:0006552 IDA
    L-leucine catabolic process GO:0006552 IEA
    L-leucine catabolic process GO:0006552 ISO
    branched-chain amino acid catabolic process GO:0009083 ISO
    fatty acid beta-oxidation using acyl-CoA dehydrogenase GO:0033539 IC
    fatty acid beta-oxidation using acyl-CoA dehydrogenase GO:0033539 ISO
    carboxylic acid catabolic process GO:0046395 IEA
Subcellular Localization
    nucleoplasm GO:0005654 IEA
    nucleoplasm GO:0005654 ISO
    mitochondrion GO:0005739 IBA
    mitochondrion GO:0005739 IEA
    mitochondrion GO:0005739 ISO
    mitochondrial matrix GO:0005759 IDA
    mitochondrial membrane GO:0031966 IDA
 Experiment description of studies that identified Ivd in sEVs
1
Experiment ID 225
MISEV standards
EM
Biophysical techniques
GAPDH|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors "Lee JE, Moon PG, Lee IK, Baek MC"
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Ivd
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Mib1  
Affinity Capture-MS Rattus norvegicus
View the network image/svg+xml
 Pathways in which Ivd is involved
PathwayEvidenceSource
Branched-chain amino acid catabolism IEA Reactome
Metabolism IEA Reactome
Metabolism of amino acids and derivatives IEA Reactome





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