Gene description for Vasn
Gene name vasorin
Gene symbol Vasn
Other names/aliases 2610528G05Rik
Atia
Slitl2
Species Mus musculus
 Database cross references - Vasn
ExoCarta ExoCarta_246154
Vesiclepedia VP_246154
Entrez Gene 246154
UniProt Q9CZT5  
 Vasn identified in sEVs derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Vasn
Molecular Function
    protein binding GO:0005515 IPI
    transforming growth factor beta binding GO:0050431 IBA
    transforming growth factor beta binding GO:0050431 IEA
    transforming growth factor beta binding GO:0050431 ISO
Biological Process
    negative regulation of epithelial to mesenchymal transition GO:0010719 IEA
    negative regulation of epithelial to mesenchymal transition GO:0010719 ISO
    negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 IBA
    negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 IEA
    negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 ISO
    cellular response to hypoxia GO:0071456 IMP
    cellular response to redox state GO:0071461 IMP
Subcellular Localization
    extracellular space GO:0005615 IBA
    extracellular space GO:0005615 ISO
    mitochondrion GO:0005739 IDA
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 IDA
    cell surface GO:0009986 IEA
    cell surface GO:0009986 ISO
    extracellular matrix GO:0031012 IBA
    extracellular exosome GO:0070062 IEA
    extracellular exosome GO:0070062 ISO
 Experiment description of studies that identified Vasn in sEVs
1
Experiment ID 210
MISEV standards
EM
Biophysical techniques
CD81|FLOT1
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors "Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL."
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Vasn
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Rnf31  
Co-fractionation Mus musculus
View the network image/svg+xml
 Pathways in which Vasn is involved
No pathways found





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