Gene description for Myo1g
Gene name myosin IG
Gene symbol Myo1g
Other names/aliases E430002D17Rik
Species Mus musculus
 Database cross references - Myo1g
ExoCarta ExoCarta_246177
Entrez Gene 246177
UniProt Q5SUA5  
 Myo1g identified in exosomes derived from the following tissue/cell type
Macrophages 23658846    
Macrophages 23658846    
Macrophages 23658846    
 Gene ontology annotations for Myo1g
Molecular Function
    calmodulin binding GO:0005516 IEA
    phosphatidylinositol-3,4,5-trisphosphate binding GO:0005547 IDA
    lipid binding GO:0008289 IEA
    nucleotide binding GO:0000166 IEA
    motor activity GO:0003774 TAS
    ATP binding GO:0005524 IEA
    actin binding GO:0003779 IEA
    phosphatidylinositol-3,4-bisphosphate binding GO:0043325 IDA
    phosphatidylinositol-4,5-bisphosphate binding GO:0005546 IDA
Biological Process
    immune system process GO:0002376 IEA
    cell gliding GO:0071976 IMP
    T cell mediated immunity GO:0002456 IMP
    Fc-gamma receptor signaling pathway involved in phagocytosis GO:0038096 IMP
    T cell migration GO:0072678 IMP
    cell-substrate adhesion GO:0031589 IMP
    exocytosis GO:0006887 IMP
    phagocytosis GO:0006909 IMP
Subcellular Localization
    cell projection GO:0042995 IEA
    cell GO:0005623 IMP
    phagocytic cup GO:0001891 IDA
    lamellipodium GO:0030027 IDA
    plasma membrane GO:0005886 ISO
    myosin complex GO:0016459 IEA
    filopodium GO:0030175 IDA
    microvillus GO:0005902 IDA
    membrane GO:0016020 ISO
    leading edge membrane GO:0031256 IDA
    extracellular exosome GO:0070062 ISO
 Experiment description of studies that identified Myo1g in exosomes
1
Experiment ID 214
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23658846    
Organism Mus musculus
Experiment description Immunomodulatory impact of leishmania-induced macrophage exosomes: a comparative proteomic and functional analysis.
Authors Hassani K, Olivier M.
Journal name PLoS Negl Trop Dis
Publication year 2013
Sample Macrophages
Sample name Leishmania-infected-Macrophage (J774A.1)
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Filtration
Protease inhibitors
Sucrose density gradient
Filtration
Ultracentrifugation
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 215
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23658846    
Organism Mus musculus
Experiment description Immunomodulatory impact of leishmania-induced macrophage exosomes: a comparative proteomic and functional analysis.
Authors Hassani K, Olivier M.
Journal name PLoS Negl Trop Dis
Publication year 2013
Sample Macrophages
Sample name LPS-treated-Macrophage (J774A.1)
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Filtration
Protease inhibitors
Sucrose density gradient
Filtration
Ultracentrifugation
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
3
Experiment ID 216
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23658846    
Organism Mus musculus
Experiment description Immunomodulatory impact of leishmania-induced macrophage exosomes: a comparative proteomic and functional analysis.
Authors Hassani K, Olivier M.
Journal name PLoS Negl Trop Dis
Publication year 2013
Sample Macrophages
Sample name Normal-Macrophage (J774A.1)
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Filtration
Protease inhibitors
Sucrose density gradient
Filtration
Ultracentrifugation
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Myo1g
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Myo1g is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here