Gene description for Prpf19
Gene name	pre-mRNA processing factor 19
Gene symbol	Prpf19
Other names/aliases	Prp19
Species	Rattus norvegicus
Database cross references - Prpf19
ExoCarta	ExoCarta_246216
Entrez Gene	246216
UniProt	Q9JMJ4
Prpf19 identified in exosomes derived from the following tissue/cell type
Reticulocytes	21828046

Gene ontology annotations for Prpf19

Molecular Function     ligase activity GO:0016874 IEA     identical protein binding GO:0042802 ISO     ubiquitin protein ligase activity GO:0061630 ISS     protein binding GO:0005515 IPI     ubiquitin-protein transferase activity GO:0004842 IBA     ubiquitin-ubiquitin ligase activity GO:0034450 ISO Biological Process     inner cell mass cell proliferation GO:0001833 ISO     positive regulation of astrocyte differentiation GO:0048711 ISO     cellular protein localization GO:0034613 ISS     mRNA splicing, via spliceosome GO:0000398 ISS     signal transduction involved in DNA damage checkpoint GO:0072422 ISS     proteasomal protein catabolic process GO:0010498 ISS     double-strand break repair via nonhomologous end joining GO:0006303 ISS     protein K63-linked ubiquitination GO:0070534 ISS     spliceosomal tri-snRNP complex assembly GO:0000244 ISS     protein polyubiquitination GO:0000209 ISO     positive regulation of mRNA splicing, via spliceosome GO:0048026 ISO     spliceosomal complex assembly GO:0000245 ISO     negative regulation of neuron differentiation GO:0045665 ISO     lipid biosynthetic process GO:0008610 ISO     generation of catalytic spliceosome for first transesterification step GO:0000349 IBA Subcellular Localization     cytoplasm GO:0005737 ISS     lipid particle GO:0005811 ISO     U2-type catalytic step 1 spliceosome GO:0071006 IBA     nuclear speck GO:0016607 ISS     nucleus GO:0005634 ISS     catalytic step 2 spliceosome GO:0071013 ISO     Prp19 complex GO:0000974 ISS     spindle GO:0005819 IEA     site of double-strand break GO:0035861 ISS     nucleoplasm GO:0005654 ISO     membrane GO:0016020 ISO     spliceosomal complex GO:0005681 ISO     DNA replication factor A complex GO:0005662 ISS