Gene description for Tax1bp1
Gene name Tax1 (human T-cell leukemia virus type I) binding protein 1
Gene symbol Tax1bp1
Other names/aliases Aa1076
Species Rattus norvegicus
 Database cross references - Tax1bp1
ExoCarta ExoCarta_246244
Vesiclepedia VP_246244
Entrez Gene 246244
UniProt Q66HA4  
 Tax1bp1 identified in sEVs derived from the following tissue/cell type
Reticulocytes 21828046    
Reticulocytes 21828046    
 Gene ontology annotations for Tax1bp1
Molecular Function
    kinase binding GO:0019900 ISO
    protein-macromolecule adaptor activity GO:0030674 ISO
    metal ion binding GO:0046872 IEA
Biological Process
    apoptotic process GO:0006915 IEA
    negative regulation of NF-kappaB transcription factor activity GO:0032088 ISO
    negative regulation of toll-like receptor 4 signaling pathway GO:0034144 ISO
    negative regulation of cytoplasmic pattern recognition receptor signaling pathway GO:0039532 ISO
    negative regulation of apoptotic process GO:0043066 IBA
    negative regulation of apoptotic process GO:0043066 IMP
    protein localization to phagocytic vesicle GO:1905161 ISO
Subcellular Localization
    phagophore assembly site GO:0000407 IEA
    mitochondrion GO:0005739 ISO
    autophagosome GO:0005776 IEA
    cytoplasmic vesicle GO:0031410 IEA
 Experiment description of studies that identified Tax1bp1 in sEVs
1
Experiment ID 90
MISEV standards
EM
Biophysical techniques
HSC70|HSP90|TSG101|MHCI
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E"
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D2 Rep 1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
2
Experiment ID 97
MISEV standards
EM
Biophysical techniques
TSG101|HSP90|HSC70|MHCI
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E."
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D4 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Tax1bp1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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