Gene description for Retsat
Gene name retinol saturase (all trans retinol 13,14 reductase)
Gene symbol Retsat
Other names/aliases Rmt7
Species Rattus norvegicus
 Database cross references - Retsat
ExoCarta ExoCarta_246298
Entrez Gene 246298
UniProt Q8VHE9  
 Retsat identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
Hepatocytes 19367702    
 Gene ontology annotations for Retsat
Molecular Function
    oxidoreductase activity GO:0016491 ISS
    all-trans-retinol 13,14-reductase activity GO:0051786 ISS
Biological Process
    retinol metabolic process GO:0042572 ISS
    oxidation-reduction process GO:0055114 ISS
Subcellular Localization
    endoplasmic reticulum membrane GO:0005789 ISS
    membrane GO:0016020 ISO
    nuclear membrane GO:0031965 ISS
    nuclear outer membrane GO:0005640 ISS
 Experiment description of studies that identified Retsat in exosomes
1
Experiment ID 225
ISEV standards
EM
EV Biophysical techniques
GAPDH
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
2
Experiment ID 35
ISEV standards
CEM
EV Biophysical techniques
TSG101|Alix
EV Cytosolic markers
CD81|CD63
EV Membrane markers
HSPA5
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19367702    
Organism Rattus norvegicus
Experiment description Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes.
Authors Conde-Vancells J, Rodriguez-Suarez E, Embade N, Gil D, Matthiesen R, Valle M, Elortza F, Lu SC, Mato JM, Falcon-Perez JM
Journal name JPR
Publication year 2008
Sample Hepatocytes
Sample name Hepatocytes
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
 Protein-protein interactions for Retsat
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Retsat is involved
No pathways found





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