Gene description for Serpina1
Gene name	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
Gene symbol	Serpina1
Other names/aliases	AAT Pi Spi1
Species	Rattus norvegicus
Database cross references - Serpina1
ExoCarta	ExoCarta_24648
Vesiclepedia	VP_24648
Entrez Gene	24648
UniProt	P17475
Serpina1 identified in sEVs derived from the following tissue/cell type
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046

Gene ontology annotations for Serpina1

Molecular Function     protease binding GO:0002020 IEA     protease binding GO:0002020 ISO     endopeptidase inhibitor activity GO:0004866 IDA     serine-type endopeptidase inhibitor activity GO:0004867 IDA     serine-type endopeptidase inhibitor activity GO:0004867 IEA     serine-type endopeptidase inhibitor activity GO:0004867 ISO     protein binding GO:0005515 IPI     identical protein binding GO:0042802 IEA     identical protein binding GO:0042802 ISO Biological Process     response to hypoxia GO:0001666 IEP     acute-phase response GO:0006953 IEA     response to lead ion GO:0010288 IDA     response to organic cyclic compound GO:0014070 IEP     response to estradiol GO:0032355 IEP     response to lipopolysaccharide GO:0032496 IEP     response to methanol GO:0033986 IDA     response to triglyceride GO:0034014 IEP     response to cytokine GO:0034097 IEA     response to cytokine GO:0034097 IEP     response to chromate GO:0046687 IDA     negative regulation of serine-type endopeptidase activity GO:1900004 IDA Subcellular Localization     extracellular space GO:0005615 IBA     extracellular space GO:0005615 IDA     extracellular space GO:0005615 IEA     extracellular space GO:0005615 ISO     endoplasmic reticulum GO:0005783 IEA     endoplasmic reticulum GO:0005783 ISO     Golgi apparatus GO:0005794 IEA     Golgi apparatus GO:0005794 ISO     intracellular membrane-bounded organelle GO:0043231 ISO