Gene description for Ppm1a
Gene name	protein phosphatase, Mg2+/Mn2+ dependent, 1A
Gene symbol	Ppm1a
Other names/aliases	Pp2c1
Species	Rattus norvegicus
Database cross references - Ppm1a
ExoCarta	ExoCarta_24666
Vesiclepedia	VP_24666
Entrez Gene	24666
UniProt	P20650
Ppm1a identified in sEVs derived from the following tissue/cell type
Reticulocytes	21828046

Gene ontology annotations for Ppm1a

Molecular Function     magnesium ion binding GO:0000287 IEA     phosphoprotein phosphatase activity GO:0004721 IDA     phosphoprotein phosphatase activity GO:0004721 ISO     protein serine/threonine phosphatase activity GO:0004722 IBA     protein serine/threonine phosphatase activity GO:0004722 ISO     protein binding GO:0005515 IPI     myosin phosphatase activity GO:0017018 IEA     manganese ion binding GO:0030145 IEA     calmodulin-dependent protein phosphatase activity GO:0033192 IEA     calmodulin-dependent protein phosphatase activity GO:0033192 ISO     transmembrane transporter binding GO:0044325 IDA     R-SMAD binding GO:0070412 IEA     R-SMAD binding GO:0070412 ISO     R-SMAD binding GO:0070412 ISS     histone H2AXS140 phosphatase activity GO:0140791 IEA     RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity GO:0180004 IEA     RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity GO:0180005 IEA     RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity GO:0180006 IEA     RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity GO:0180007 IEA     RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity GO:0180008 IEA     MAP kinase serine/threonine phosphatase activity GO:1990439 IEA Biological Process     chromatin remodeling GO:0006338 IEA     regulation of transcription by RNA polymerase II GO:0006357 IEA     protein dephosphorylation GO:0006470 ISO     protein dephosphorylation GO:0006470 ISO     protein dephosphorylation GO:0006470 ISS     N-terminal protein myristoylation GO:0006499 ISO     N-terminal protein myristoylation GO:0006499 ISS     protein export from nucleus GO:0006611 IEA     protein export from nucleus GO:0006611 ISO     dephosphorylation GO:0016311 ISO     negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 IEA     negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 ISO     negative regulation of BMP signaling pathway GO:0030514 IEA     negative regulation of BMP signaling pathway GO:0030514 ISO     peptidyl-threonine dephosphorylation GO:0035970 ISO     regulation of canonical NF-kappaB signal transduction GO:0043122 IBA     positive regulation of canonical NF-kappaB signal transduction GO:0043123 ISO     negative regulation of canonical NF-kappaB signal transduction GO:0043124 IEA     negative regulation of canonical NF-kappaB signal transduction GO:0043124 ISO     negative regulation of canonical NF-kappaB signal transduction GO:0043124 ISS     positive regulation of DNA-templated transcription GO:0045893 IEA     positive regulation of DNA-templated transcription GO:0045893 ISO     positive regulation of protein export from nucleus GO:0046827 IEA     positive regulation of protein export from nucleus GO:0046827 ISO     cellular response to transforming growth factor beta stimulus GO:0071560 IEA     cellular response to transforming growth factor beta stimulus GO:0071560 ISO     positive regulation of canonical Wnt signaling pathway GO:0090263 IBA     positive regulation of canonical Wnt signaling pathway GO:0090263 IEA     positive regulation of canonical Wnt signaling pathway GO:0090263 ISO     negative regulation of non-canonical NF-kappaB signal transduction GO:1901223 IEA     negative regulation of non-canonical NF-kappaB signal transduction GO:1901223 ISO     negative regulation of non-canonical NF-kappaB signal transduction GO:1901223 ISS Subcellular Localization     nucleus GO:0005634 IBA     nucleus GO:0005634 IEA     nucleus GO:0005634 ISO     cytosol GO:0005829 IBA     cytosol GO:0005829 IEA     cytosol GO:0005829 ISO     cytosol GO:0005829 ISS     plasma membrane GO:0005886 IEA     plasma membrane GO:0005886 ISO     membrane GO:0016020 ISO     membrane GO:0016020 ISS     neuron projection GO:0043005 IDA