Gene description for Prnp
Gene name	prion protein
Gene symbol	Prnp
Other names/aliases	PrP Prn
Species	Rattus norvegicus
Database cross references - Prnp
ExoCarta	ExoCarta_24686
Entrez Gene	24686
UniProt	P13852
Prnp identified in exosomes derived from the following tissue/cell type
Reticulocytes	21828046
Reticulocytes	21828046

Gene ontology annotations for Prnp

Molecular Function     ion channel binding GO:0044325 IPI     tubulin binding GO:0015631 ISO     chaperone binding GO:0051087 IPI     copper ion binding GO:0005507 TAS     ATP-dependent protein binding GO:0043008 IPI     microtubule binding GO:0008017 ISO     identical protein binding GO:0042802 ISO Biological Process     negative regulation of interleukin-17 production GO:0032700 ISO     negative regulation of T cell receptor signaling pathway GO:0050860 ISO     negative regulation of protein phosphorylation GO:0001933 ISO     cellular response to copper ion GO:0071280 ISO     cellular response to drug GO:0035690 ISO     negative regulation of sequence-specific DNA binding transcription factor activity GO:0043433 ISO     response to copper ion GO:0046688 IDA     protein homooligomerization GO:0051260 IEA     regulation of protein localization GO:0032880 ISO     response to cadmium ion GO:0046686 IDA     learning or memory GO:0007611 IMP     response to oxidative stress GO:0006979 ISO     negative regulation of interferon-gamma production GO:0032689 ISO     negative regulation of activated T cell proliferation GO:0046007 ISO     negative regulation of calcineurin-NFAT signaling cascade GO:0070885 ISO     negative regulation of apoptotic process GO:0043066 ISO     regulation of potassium ion transmembrane transport GO:1901379 ISO     negative regulation of interleukin-2 production GO:0032703 ISO Subcellular Localization     Golgi apparatus GO:0005794 ISO     anchored component of plasma membrane GO:0046658 TAS     extracellular exosome GO:0070062 ISO     cytoplasm GO:0005737 IDA     plasma membrane GO:0005886 ISO     cell surface GO:0009986 TAS     mitochondrial outer membrane GO:0005741 ISO     membrane GO:0016020 ISO     membrane raft GO:0045121 ISS     endoplasmic reticulum GO:0005783 ISO