Gene description for Prss1
Gene name protease, serine, 1 (trypsin 1)
Gene symbol Prss1
Other names/aliases PTRYI
RATPTRYI
Try1
Species Rattus norvegicus
 Database cross references - Prss1
ExoCarta ExoCarta_24691
Vesiclepedia VP_24691
Entrez Gene 24691
UniProt P00762  
 Prss1 identified in sEVs derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Prss1
Molecular Function
    serine-type endopeptidase activity GO:0004252 IBA
    metal ion binding GO:0046872 IEA
Biological Process
    proteolysis GO:0006508 IBA
    response to nutrient GO:0007584 IEP
    digestion GO:0007586 IEA
    response to caffeine GO:0031000 IDA
    response to nicotine GO:0035094 IDA
    response to acetaldehyde GO:1905640 IEP
Subcellular Localization
    extracellular space GO:0005615 IBA
    extracellular space GO:0005615 IDA
 Experiment description of studies that identified Prss1 in sEVs
1
Experiment ID 225
MISEV standards
✔
EM
Biophysical techniques
✔
GAPDH|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors "Lee JE, Moon PG, Lee IK, Baek MC"
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Prss1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Mib1  
Affinity Capture-MS Rattus norvegicus
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here