Gene description for Sparc
Gene name	secreted protein, acidic, cysteine-rich (osteonectin)
Gene symbol	Sparc
Other names/aliases	-
Species	Rattus norvegicus
Database cross references - Sparc
ExoCarta	ExoCarta_24791
Vesiclepedia	VP_24791
Entrez Gene	24791
UniProt	P16975
Sparc identified in sEVs derived from the following tissue/cell type
Adipocytes	25998041

Gene ontology annotations for Sparc

Molecular Function     calcium ion binding GO:0005509 IBA     calcium ion binding GO:0005509 IDA     calcium ion binding GO:0005509 IEA     calcium ion binding GO:0005509 ISO     collagen binding GO:0005518 IBA     collagen binding GO:0005518 IEA     collagen binding GO:0005518 ISO     extracellular matrix binding GO:0050840 IBA     extracellular matrix binding GO:0050840 ISO Biological Process     ossification GO:0001503 IEP     negative regulation of endothelial cell proliferation GO:0001937 IEA     negative regulation of endothelial cell proliferation GO:0001937 ISO     heart development GO:0007507 IEP     response to gravity GO:0009629 IEP     response to lead ion GO:0010288 IEP     positive regulation of endothelial cell migration GO:0010595 IEA     positive regulation of endothelial cell migration GO:0010595 ISO     negative regulation of angiogenesis GO:0016525 IEA     negative regulation of angiogenesis GO:0016525 ISO     regulation of cell morphogenesis GO:0022604 IEA     regulation of cell morphogenesis GO:0022604 ISO     lung development GO:0030324 IMP     response to lipopolysaccharide GO:0032496 IEP     response to L-ascorbic acid GO:0033591 IEP     response to cytokine GO:0034097 IEP     regulation of cell population proliferation GO:0042127 ISO     response to peptide hormone GO:0043434 IEP     pigmentation GO:0043473 ISO     response to ethanol GO:0045471 IEP     response to cadmium ion GO:0046686 IEP     semicircular canal morphogenesis GO:0048752 IBA     inner ear development GO:0048839 IEP     regulation of synapse organization GO:0050807 EXP     regulation of synapse organization GO:0050807 IBA     regulation of synapse organization GO:0050807 IDA     response to glucocorticoid GO:0051384 IEP     response to cAMP GO:0051591 IEP     response to calcium ion GO:0051592 IEP     bone development GO:0060348 ISO     cellular response to growth factor stimulus GO:0071363 ISO Subcellular Localization     basement membrane GO:0005604 IEA     extracellular space GO:0005615 IBA     extracellular space GO:0005615 IDA     extracellular space GO:0005615 IEA     extracellular space GO:0005615 ISO     cytoplasm GO:0005737 ISO     cytoplasm GO:0005737 ISO     mitochondrion GO:0005739 ISO     plasma membrane GO:0005886 ISO     cell surface GO:0009986 IEA     cell surface GO:0009986 ISO     nuclear matrix GO:0016363 IEA     nuclear matrix GO:0016363 ISO     extracellular matrix GO:0031012 ISO     platelet alpha granule GO:0031091 ISO     platelet alpha granule membrane GO:0031092 IEA     platelet alpha granule membrane GO:0031092 ISO     vesicle GO:0031982 IDA     intracellular membrane-bounded organelle GO:0043231 ISO     synapse GO:0045202 EXP     synapse GO:0045202 IDA     glutamatergic synapse GO:0098978 EXP     glutamatergic synapse GO:0098978 IDA