Gene description for Hist1h2ba
Gene name histone cluster 1, H2ba
Gene symbol Hist1h2ba
Other names/aliases Th2b
Species Rattus norvegicus
 Database cross references - Hist1h2ba
ExoCarta ExoCarta_24829
Entrez Gene 24829
UniProt Q00729  
 Hist1h2ba identified in exosomes derived from the following tissue/cell type
Hepatocytes 19367702    
 Gene ontology annotations for Hist1h2ba
Molecular Function
    protein heterodimerization activity GO:0046982 IEA
    DNA binding GO:0003677 IDA
Biological Process
    inflammatory response GO:0006954 ISO
    positive regulation of binding GO:0051099 ISO
    spermatogenesis, exchange of chromosomal proteins GO:0035093 ISS
    nucleosome assembly GO:0006334 ISS
    chromatin organization GO:0006325 ISO
    plasminogen activation GO:0031639 ISO
    mononuclear cell migration GO:0071674 ISO
    nucleosome disassembly GO:0006337 ISS
Subcellular Localization
    extrinsic component of plasma membrane GO:0019897 ISO
    nucleus GO:0005634 ISO
    nucleosome GO:0000786 ISS
    nuclear nucleosome GO:0000788 IBA
 Experiment description of studies that identified Hist1h2ba in exosomes
1
Experiment ID 35
ISEV standards
✔
CEM
EV Biophysical techniques
✔
TSG101|Alix
EV Cytosolic markers
✔
CD81|CD63
EV Membrane markers
✔
HSPA5
EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19367702    
Organism Rattus norvegicus
Experiment description Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes.
Authors Conde-Vancells J, Rodriguez-Suarez E, Embade N, Gil D, Matthiesen R, Valle M, Elortza F, Lu SC, Mato JM, Falcon-Perez JM
Journal name JPR
Publication year 2008
Sample Hepatocytes
Sample name Hepatocytes
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
 Protein-protein interactions for Hist1h2ba
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Hist1h2ba is involved
PathwayEvidenceSource
HATs acetylate histones IEA Reactome





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here