Gene description for Ugt1a1
Gene name UDP glucuronosyltransferase 1 family, polypeptide A1
Gene symbol Ugt1a1
Other names/aliases UDPGT 1-1
Udpgt
Ugt1
Species Rattus norvegicus
 Database cross references - Ugt1a1
ExoCarta ExoCarta_24861
Vesiclepedia VP_24861
Entrez Gene 24861
UniProt Q64550  
 Ugt1a1 identified in sEVs derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Ugt1a1
Molecular Function
    retinoic acid binding GO:0001972 ISO
    enzyme inhibitor activity GO:0004857 ISO
    steroid binding GO:0005496 ISO
    glucuronosyltransferase activity GO:0015020 IDA
    glucuronosyltransferase activity GO:0015020 ISO
    enzyme binding GO:0019899 IBA
    enzyme binding GO:0019899 IDA
    enzyme binding GO:0019899 ISO
    protein homodimerization activity GO:0042803 ISO
    protein heterodimerization activity GO:0046982 ISO
Biological Process
    liver development GO:0001889 IEP
    bilirubin conjugation GO:0006789 TAS
    acute-phase response GO:0006953 IEP
    response to nutrient GO:0007584 IEP
    estrogen metabolic process GO:0008210 ISO
    response to xenobiotic stimulus GO:0009410 IEP
    response to organic cyclic compound GO:0014070 IEP
    animal organ regeneration GO:0031100 IEP
    response to lipopolysaccharide GO:0032496 IEP
    cellular response to hormone stimulus GO:0032870 IEP
    response to starvation GO:0042594 IEP
    response to ethanol GO:0045471 IEP
    response to steroid hormone GO:0048545 IEP
    response to glucocorticoid GO:0051384 IEP
    flavone metabolic process GO:0051552 ISO
    cellular glucuronidation GO:0052695 IBA
    cellular glucuronidation GO:0052695 IDA
    cellular glucuronidation GO:0052695 ISO
    flavonoid glucuronidation GO:0052696 IDA
    flavonoid glucuronidation GO:0052696 ISO
    xenobiotic glucuronidation GO:0052697 IDA
    xenobiotic glucuronidation GO:0052697 ISO
    biphenyl catabolic process GO:0070980 IDA
    cellular response to ethanol GO:0071361 IEP
    cellular response to glucocorticoid stimulus GO:0071385 IEP
    cellular response to estradiol stimulus GO:0071392 IEP
    cellular response to xenobiotic stimulus GO:0071466 IEP
    negative regulation of cellular glucuronidation GO:2001030 ISO
Subcellular Localization
    endoplasmic reticulum GO:0005783 IBA
    endoplasmic reticulum GO:0005783 IDA
    endoplasmic reticulum GO:0005783 ISO
    endoplasmic reticulum membrane GO:0005789 IEA
    plasma membrane GO:0005886 ISO
    endoplasmic reticulum chaperone complex GO:0034663 ISO
    cytochrome complex GO:0070069 IDA
 Experiment description of studies that identified Ugt1a1 in sEVs
1
Experiment ID 225
MISEV standards
EM
Biophysical techniques
GAPDH|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors "Lee JE, Moon PG, Lee IK, Baek MC"
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
2
Experiment ID 225
MISEV standards
EM
Biophysical techniques
GAPDH|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors "Lee JE, Moon PG, Lee IK, Baek MC"
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Ugt1a1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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