Gene description for Atp7a
Gene name	ATPase, Cu++ transporting, alpha polypeptide
Gene symbol	Atp7a
Other names/aliases	Mnk
Species	Rattus norvegicus
Database cross references - Atp7a
ExoCarta	ExoCarta_24941
Entrez Gene	24941
UniProt	P70705
Atp7a identified in exosomes derived from the following tissue/cell type
Reticulocytes	21828046

Gene ontology annotations for Atp7a

Molecular Function     copper-exporting ATPase activity GO:0004008 ISO     ATP binding GO:0005524 IEA     metal ion binding GO:0046872 IEA     superoxide dismutase copper chaperone activity GO:0016532 ISO     copper ion transmembrane transporter activity GO:0005375 ISO     molecular_function GO:0003674 ND     copper-dependent protein binding GO:0032767 ISO     copper ion binding GO:0005507 ISO Biological Process     central nervous system neuron development GO:0021954 ISO     response to copper ion GO:0046688 IDA     negative regulation of metalloenzyme activity GO:0048553 ISO     neuron projection morphogenesis GO:0048812 ISO     positive regulation of oxidoreductase activity GO:0051353 ISO     detoxification of copper ion GO:0010273 ISO     pigmentation GO:0043473 ISO     hair follicle morphogenesis GO:0031069 ISO     norepinephrine biosynthetic process GO:0042421 ISO     regulation of gene expression GO:0010468 ISO     tyrosine metabolic process GO:0006570 ISO     pyramidal neuron development GO:0021860 ISO     blood vessel development GO:0001568 ISO     norepinephrine metabolic process GO:0042415 ISO     elastin biosynthetic process GO:0051542 ISO     negative regulation of neuron apoptotic process GO:0043524 ISO     epinephrine metabolic process GO:0042414 ISO     lung alveolus development GO:0048286 ISO     extracellular matrix organization GO:0030198 ISO     metal ion transport GO:0030001 IEA     response to zinc ion GO:0010043 IEP     blood vessel remodeling GO:0001974 ISO     removal of superoxide radicals GO:0019430 ISO     peptidyl-lysine modification GO:0018205 ISO     T-helper cell differentiation GO:0042093 ISO     locomotory behavior GO:0007626 ISO     cerebellar Purkinje cell differentiation GO:0021702 ISO     collagen fibril organization GO:0030199 ISO     plasma membrane copper ion transport GO:0015679 IMP     response to iron(III) ion GO:0010041 IEP     dopamine metabolic process GO:0042417 ISO     lactation GO:0007595 IEP     catecholamine metabolic process GO:0006584 ISO     regulation of oxidative phosphorylation GO:0002082 ISO     tryptophan metabolic process GO:0006568 ISO     release of cytochrome c from mitochondria GO:0001836 ISO     ATP metabolic process GO:0046034 ISO     copper ion import GO:0015677 ISO     elastic fiber assembly GO:0048251 ISO     cellular copper ion homeostasis GO:0006878 ISO     mitochondrion organization GO:0007005 ISO     cartilage development GO:0051216 ISO     serotonin metabolic process GO:0042428 ISO     positive regulation of catalytic activity GO:0043085 ISO     copper ion export GO:0060003 ISO     in utero embryonic development GO:0001701 IEP     copper ion transport GO:0006825 ISO     hindlimb morphogenesis GO:0035137 ISO     dendrite morphogenesis GO:0048813 ISO     positive regulation of metalloenzyme activity GO:0048554 ISO     skin development GO:0043588 ISO Subcellular Localization     secretory granule GO:0030141 IDA     basolateral plasma membrane GO:0016323 ISO     perinuclear region of cytoplasm GO:0048471 ISO     integral component of membrane GO:0016021 IDA     endoplasmic reticulum GO:0005783 ISO     cytoplasmic vesicle GO:0031410 ISO     trans-Golgi network GO:0005802 ISO     plasma membrane GO:0005886 ISO     cell GO:0005623 ISO     trans-Golgi network transport vesicle GO:0030140 ISO     late endosome GO:0005770 ISO     neuronal cell body GO:0043025 ISO     membrane GO:0016020 ISO     Golgi apparatus GO:0005794 ISO     neuron projection GO:0043005 ISO     brush border membrane GO:0031526 IDA