Gene description for Kng2
Gene name kininogen 2
Gene symbol Kng2
Other names/aliases KINKG
KINKH
Kng1
Kngk
Species Rattus norvegicus
 Database cross references - Kng2
ExoCarta ExoCarta_25087
Entrez Gene 25087
UniProt P08934  
 Kng2 identified in exosomes derived from the following tissue/cell type
Hepatocytes 19367702    
 Gene ontology annotations for Kng2
Molecular Function
    cysteine-type endopeptidase inhibitor activity GO:0004869 IEA
Biological Process
    vasodilation GO:0042311 IEA
    inflammatory response GO:0006954 IEA
    negative regulation of endopeptidase activity GO:0010951 IEA
    blood coagulation GO:0007596 IEA
 Experiment description of studies that identified Kng2 in exosomes
1
Experiment ID 35
ISEV standards
CEM
EV Biophysical techniques
TSG101|Alix
EV Cytosolic markers
CD81|CD63
EV Membrane markers
HSPA5
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19367702    
Organism Rattus norvegicus
Experiment description Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes.
Authors Conde-Vancells J, Rodriguez-Suarez E, Embade N, Gil D, Matthiesen R, Valle M, Elortza F, Lu SC, Mato JM, Falcon-Perez JM
Journal name JPR
Publication year 2008
Sample Hepatocytes
Sample name Hepatocytes
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
 Protein-protein interactions for Kng2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Kng2 is involved
No pathways found





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