Gene description for Hsd11b1
Gene name	hydroxysteroid 11-beta dehydrogenase 1
Gene symbol	Hsd11b1
Other names/aliases	LRRGT00065
Species	Rattus norvegicus
Database cross references - Hsd11b1
ExoCarta	ExoCarta_25116
Vesiclepedia	VP_25116
Entrez Gene	25116
UniProt	P16232
Hsd11b1 identified in sEVs derived from the following tissue/cell type
Hepatocytes	19367702

Gene ontology annotations for Hsd11b1

Molecular Function     steroid binding GO:0005496 IBA     steroid binding GO:0005496 IPI     oxidoreductase activity GO:0016491 IEA     protein homodimerization activity GO:0042803 ISO     7-beta-hydroxysteroid dehydrogenase (NADP+) activity GO:0047022 IEA     NADP binding GO:0050661 IDA     NADP binding GO:0050661 ISO     11-beta-hydroxysteroid dehydrogenase (NADP+) activity GO:0070524 IBA     11-beta-hydroxysteroid dehydrogenase (NADP+) activity GO:0070524 ISO Biological Process     glucocorticoid biosynthetic process GO:0006704 IDA     steroid catabolic process GO:0006706 IBA     glucocorticoid catabolic process GO:0006713 IDA     mineralocorticoid metabolic process GO:0008212 IDA     lung development GO:0030324 ISO     response to nutrient levels GO:0031667 IEP     regulation of pentose-phosphate shunt GO:0043456 IDA     cellular response to estradiol stimulus GO:0071392 IEP Subcellular Localization     endoplasmic reticulum membrane GO:0005789 IBA     endoplasmic reticulum membrane GO:0005789 IEA     endoplasmic reticulum membrane GO:0005789 ISO     nuclear membrane GO:0031965 IDA     intracellular membrane-bounded organelle GO:0043231 IBA     apical part of cell GO:0045177 IDA