Gene description for Tapbp
Gene name TAP binding protein (tapasin)
Gene symbol Tapbp
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Tapbp
ExoCarta ExoCarta_25217
Entrez Gene 25217
 Tapbp identified in exosomes derived from the following tissue/cell type
Reticulocytes 21828046    
Reticulocytes 21828046    
 Gene ontology annotations for Tapbp
Molecular Function
    TAP1 binding GO:0046978 ISO
    unfolded protein binding GO:0051082 NAS
    TAP2 binding GO:0046979 ISO
Biological Process
    peptide antigen stabilization GO:0050823 ISO
    antigen processing and presentation of endogenous peptide antigen via MHC class I GO:0019885 IEA
    antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent GO:0002479 ISO
    defense response GO:0006952 ISO
    MHC class I protein complex assembly GO:0002397 IEP
Subcellular Localization
    Golgi membrane GO:0000139 ISO
    endoplasmic reticulum membrane GO:0005789 ISO
    TAP complex GO:0042825 ISO
    MHC class I peptide loading complex GO:0042824 IDA
 Experiment description of studies that identified Tapbp in exosomes
1
Experiment ID 90
ISEV standards
EM
EV Biophysical techniques
HSC70|HSP90|TSG101
EV Cytosolic markers
MHCI
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D2 Rep 1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
2
Experiment ID 94
ISEV standards
EM
EV Biophysical techniques
TSG101|HSP90|HSC70
EV Cytosolic markers
MHCI
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E.
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D4 Rep 1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Tapbp
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Tapbp is involved
No pathways found





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